SCHEMBL1835330

SCHEMBL1835330

Cn1c(CN(CCCC2CC(n3c(=O)[nH]c4ccccc43)CCN2C(=O)O)Cc2ccccc2)cc2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.43
PMP22 Q01453 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
BCHE P06276 1/20 0.43
ACHE P22303 1/20 0.43
OPRM1 P35372 3/20 0.41
OPRK1 P41145 2/20 0.41
OPRL1 P41146 1/20 0.41
CYP2D6 P10635 3/20 0.40
CYP2C9 P11712 1/20 0.40
PLD2 O14939 4/20 0.40
CHRM1 P11229 2/20 0.39
PLD1 Q13393 3/20 0.39
HSD11B1 P28845 1/20 0.39
MLNR O43193 1/20 0.39
LMNA P02545 1/20 0.39
PGR P06401 1/20 0.39
ADRB2 P07550 1/20 0.39
CHRM2 P08172 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3669767 0.90 BCHE (0.38) KDM4EALDH1A1PMP22NPSR1BCHE
SCHEMBL1835272 0.90 OPRM1 (0.50) KDM4EALDH1A1PMP22NPSR1BCHE
SCHEMBL3403017 0.90 OPRM1 (0.50) KDM4EALDH1A1PMP22NPSR1BCHE
SCHEMBL1834994 0.85 OPRM1 (0.52) KDM4EALDH1A1PMP22NPSR1BCHE
SCHEMBL3399651 0.85 OPRM1 (0.52) KDM4EALDH1A1PMP22NPSR1BCHE
SCHEMBL1838176 0.85 OPRK1 (0.50) KDM4EALDH1A1PMP22NPSR1BCHE
SCHEMBL1836260 0.85 OPRK1 (0.50) KDM4EALDH1A1PMP22NPSR1BCHE
SCHEMBL1834696 0.85 OPRM1 (0.41) KDM4EALDH1A1PMP22NPSR1BCHE
SCHEMBL3400375 0.85 OPRM1 (0.47) KDM4EALDH1A1PMP22NPSR1BCHE
SCHEMBL1831703 0.85 OPRM1 (0.47) KDM4EALDH1A1PMP22NPSR1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2160098-B9 USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2011-05-18 EP claimed
EP-2160098-B1 USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS COMMISSARIAT ENERGIE ATOMIQUE (FR) 2010-11-10 EP claimed