SCHEMBL1835414

SCHEMBL1835414

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(N)(=O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 7/20 0.86
P2RY2 P41231 3/20 0.86
SRC P12931 2/20 0.86
SMN1; SMN2 Q16637 2/20 0.86
TRPM2 O94759 2/20 0.86
TAS1R3 Q7RTX0 2/20 0.86
TAS1R1 Q7RTX1 2/20 0.86
DNPH1 O43598 1/20 0.86
PRKAB2 O43741 1/20 0.86
LDHA P00338 1/20 0.86
ADRB2 P07550 1/20 0.86
FBP1 P09467 1/20 0.86
ADORA1 P30542 1/20 0.86
PRKAG1 P54619 1/20 0.86
PRKAA2 P54646 1/20 0.86
PDE4D Q08499 1/20 0.86
KCNH2 Q12809 1/20 0.86
PRKAA1 Q13131 1/20 0.86
PDE3A Q14432 1/20 0.86
P2RY11 Q96G91 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine Phosphate SCHEMBL2512522 0.93 P2RY1 (0.96) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL11977309 0.93 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL19420134 0.93 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL20277555 0.93 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL144997 0.93 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL13170051 0.93 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL132458 0.93 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
SCHEMBL5055892 0.93 P2RY1 (0.92) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL8572634 0.93 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2
Adenosine Phosphate SCHEMBL1338615 0.93 P2RY1 (1.00) P2RY1P2RY2SRCSMN1; SMN2TRPM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1427425-A4 METHOD OF TREATMENT OF OBESITY AND PARALYZED MUSCLE AND ERGOGENIC AIDS UNIV BRIGHAM YOUNG (US) 2006-04-05 EP claimed
EP-1427425-A1 METHOD OF TREATMENT OF OBESITY AND PARALYZED MUSCLE AND ERGOGENIC AIDS Brigham Young University (US) 2004-06-16 EP claimed
US-20030212034-A1 Method of treatment of obesity and paralyzed muscle and ergogenic aids WINDER WILLIAM W (US) 2003-11-13 US claimed
US-20030212013-A1 Use of amp kinase activators for treatment type 2 diabetes and insulin resistance BRIGHAM YOUNG UNIVERSITY 2003-11-13 US claimed
WO-2001097816-A1 USE OF AMP KINASE ACTIVATORS FOR TREATMENT OF TYPE 2 DIABETES AND INSULIN RESISTANCE BRIGHAM YOUNG UNIVERSITY (US) 2001-12-27 WO claimed
WO-2001093874-A1 METHOD OF TREATMENT OF OBESITY AND PARALYZED MUSCLE AND ERGOGENIC AIDS BRIGHAM YOUNG UNIVERSITY (US) 2001-12-13 WO claimed
US-20250076302-A1 DETECTING THE PRESENCE OF URINARY STONE DISEASE USING A PLURALITY OF URINARY METABOLITES THE CLEVELAND CLINIC FOUNDATION 2025-03-06 US disclosed
US-20250057860-A1 READY-TO-DILUTE FORMULATION EMPHASCIENCE, INC. 2025-02-20 US disclosed
WO-2023076878-A1 READY-TO-DILUTE FORMULATION EMPHASCIENCE INC. (US) 2023-05-04 WO disclosed
US-11180523-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags QUANTUMDX GROUP LIMITED (GB) 2021-11-23 US disclosed
US-10759824-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags QUANTUMDX GROUP LIMITED (GB) 2020-09-01 US disclosed
US-20190248827-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS QUANTUMDX GROUP LIMITED (GB) 2019-08-15 US disclosed
US-10273261-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags QUANTUMDX GROUP LIMITED (GB) 2019-04-30 US disclosed
WO-1996029345-A1 NOVEL INOTROPIC AGENTS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 1996-09-26 WO disclosed
WO-1996020946-A1 FLAVIN ADENINE DINUCLEOTIDE ANALOGUES, THEIR PHARMACEUTICAL COMPOSITIONS, AND THEIR ACTIVITY AS MONOAMINE OXIDASE INHIBITORS RESEARCH DEVELOPMENT FOUNDATION (US) 1996-07-11 WO disclosed
WO-1989009283-A1 PYROPHOSPHATE-BASED METHOD AND APPARATUS FOR SEQUENCING NUCLEIC ACIDS HYMAN EDWARD DAVID (US) 1989-10-05 WO disclosed
EP-0090405-B1 NOVEL AZOLE DINUCLEOTIDE COMPOUNDS AND METHODS FOR THEIR PRODUCTION BRIGHAM YOUNG UNIVERSITY (US) 1986-06-25 EP disclosed
US-4594415-A Viricides ROBINS ROLAND K (US) 1986-06-10 US disclosed
US-4544741-A Azole dinucleotide compounds and methods for their production BRIGHAM YOUNG UNIVERSITY, PROVO, UT., A NONPROFIT CORP. OF UT 1985-10-01 US disclosed
EP-0090405-A1 Novel azole dinucleotide compounds and methods for their production BRIGHAM YOUNG UNIVERSITY (US) 1983-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250057860-A1 READY-TO-DILUTE FORMULATION PRPF6, PNP, PRNP P2RY1 299/4885P2RY2 835/4885SRC 4806/4885
US-11180523-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags POLM, RNGTT, TYMP P2RY1 2147/4885P2RY2 2556/4885SRC 3178/4885
US-10759824-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags POLM, RNGTT, TYMP P2RY1 2147/4885P2RY2 2556/4885SRC 3178/4885
US-20190248827-A1 DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES COMPRISING CHARGE MASS TAGS POLM, RNGTT, TYMP P2RY1 2147/4885P2RY2 2556/4885SRC 3178/4885
US-10273261-B2 Design, synthesis and use of synthetic nucleotides comprising charge mass tags POLM, RNGTT, TYMP P2RY1 2147/4885P2RY2 2556/4885SRC 3178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.