Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | POLB | P06746 | 7/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 7/20 | 0.56 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | MITF | O75030 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL28835365 | 1.00 | KMT2A (0.63) | KMT2APOLBTDP1L3MBTL1GLO1 | |
| Acetic Acid SCHEMBL19458526 | 0.91 | GLO1 (0.64) | KMT2APOLBTDP1L3MBTL1GLO1 | |
| SCHEMBL183545 | 0.91 | KMT2A (0.66) | KMT2APOLBTDP1L3MBTL1GLO1 | |
| Nitric Acid SCHEMBL11753070 | 0.89 | KMT2A (0.59) | KMT2APOLBTDP1L3MBTL1GLO1 | |
| Ammonia Solution, Strong SCHEMBL27671164 | 0.89 | KMT2A (0.63) | KMT2APOLBTDP1L3MBTL1GLO1 | |
| Glycine SCHEMBL8217195 | 0.87 | KMT2A (0.56) | KMT2APOLBTDP1L3MBTL1GLO1 | |
| Acetic Acid SCHEMBL11781050 | 0.85 | KMT2A (0.59) | KMT2APOLBTDP1L3MBTL1GLO1 | |
| Furan SCHEMBL28801428 | 0.81 | KMT2A (0.54) | KMT2APOLBTDP1L3MBTL1GLO1 | |
| Biguanide SCHEMBL27425059 | 0.79 | LMNA (0.52) | KMT2APOLBTDP1L3MBTL1GLO1 | |
| SCHEMBL19580101 | 0.79 | LMNA (0.52) | KMT2APOLBTDP1L3MBTL1GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1513851-A | Synthesis method of 5-hydroxy methyl furazolidone | 曹桂东 | 2004-07-21 | — | — | CN | claimed |
| CN-1513851-A | Synthesis method of 5-hydroxy methyl furazolidone | 曹桂东 | 2004-07-21 | — | — | CN | disclosed |