Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14968999 | 1.00 | MAPK1 (0.42) | MAPK1 | |
| SCHEMBL16577200 | 0.92 | MAPK1 (0.48) | MAPK1 | |
| SCHEMBL5765880 | 0.83 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL17914141 | 0.83 | MAPK1 (0.46) | MAPK1 | |
| SCHEMBL51157 | 0.81 | — | — | |
| SCHEMBL24658397 | 0.78 | MAPK1 (0.41) | MAPK1 | |
| SCHEMBL14969322 | 0.78 | MAPK1 (0.41) | MAPK1 | |
| SCHEMBL18993085 | 0.78 | MAPK1 (0.41) | MAPK1 | |
| SCHEMBL18892556 | 0.76 | MAPK1 (0.39) | MAPK1 | |
| SCHEMBL19079085 | 0.76 | PRKD3 (0.58) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11826438-B2 | Hyperbranched polyglycerol-coated particles and methods of making and using thereof | YALE UNIVERSITY (US) | 2023-11-28 | — | — | US | disclosed |
| US-20230355801-A1 | IMMUNOTHERAPY OF SKIN CANCER USING MPLA-LOADED HPG NANOPARTICLES | YALE UNIVERSITY | 2023-11-09 | — | — | US | disclosed |
| US-20180177688-A1 | TOPICAL FORMULATION OF HYPERBRANCHED POLYGLYCEROL-COATED PARTICLES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-06-28 | — | — | US | disclosed |
| US-20170266119-A1 | HYPERBRANCHED POLYGLYCEROL-COATED PARTICLES AND METHODS OF MAKING AND USING THEREOF | YALE UNIVERSITY | 2017-09-21 | — | — | US | disclosed |
| US-20170000737-A1 | HYPERBRANCHED POLYGLYCEROL-COATED PARTICLES AND METHODS OF MAKING AND USING THEREOF | YALE UNIVERSITY | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230355801-A1 | IMMUNOTHERAPY OF SKIN CANCER USING MPLA-LOADED HPG NANOPARTICLES | CD69, CD40LG, MPL | MAPK1 2069/4885 |
| US-11826438-B2 | Hyperbranched polyglycerol-coated particles and methods of making and using thereof | LIPG, CETP, LIPA | MAPK1 4328/4885 |
| US-20180177688-A1 | TOPICAL FORMULATION OF HYPERBRANCHED POLYGLYCEROL-COATED PARTICLES THEREOF | CUTA, KRTCAP2, HBG2 | MAPK1 3908/4885 |
| US-20170266119-A1 | HYPERBRANCHED POLYGLYCEROL-COATED PARTICLES AND METHODS OF MAKING AND USING THEREOF | LIPG, CETP, LIPA | MAPK1 4328/4885 |
| US-20170000737-A1 | HYPERBRANCHED POLYGLYCEROL-COATED PARTICLES AND METHODS OF MAKING AND USING THEREOF | LIPG, CETP, LIPA | MAPK1 4328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.