Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18353002 | 0.98 | L3MBTL1 (0.49) | HCAR2L3MBTL1ATMACHE | |
| SCHEMBL18355229 | 0.93 | L3MBTL1 (0.46) | HCAR2L3MBTL1ATMACHE | |
| SCHEMBL18355226 | 0.91 | HCAR2 (0.50) | HCAR2L3MBTL1ATMACHEMAPT | |
| SCHEMBL18354903 | 0.89 | ATM (0.53) | HCAR2ATMACHE | |
| SCHEMBL18353205 | 0.87 | ATM (0.55) | HCAR2ATMACHEMAPT | |
| SCHEMBL18355109 | 0.87 | HCAR2 (0.43) | HCAR2L3MBTL1ATMACHEMAPT | |
| SCHEMBL18364167 | 0.85 | HCAR2 (0.52) | HCAR2ATMMAPT | |
| SCHEMBL18354850 | 0.85 | SMN1; SMN2 (0.45) | HCAR2L3MBTL1ATMMAPT | |
| SCHEMBL18355322 | 0.85 | TDP1 (0.45) | HCAR2L3MBTL1ATMMAPT | |
| SCHEMBL18374996 | 0.84 | MAPT (0.50) | HCAR2L3MBTL1ATMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170001953-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2017-01-05 | — | — | US | disclosed |
| US-20170001953-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001953-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | FH, FPGS, APC | HCAR2 290/4885L3MBTL1 4164/4885ATM 4406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.