Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 6/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18354633 | 0.97 | MLYCD (0.39) | MLYCDRXFP1DHODHHDAC8LRRK2 | |
| SCHEMBL18356117 | 0.94 | MLYCD (0.37) | MLYCDRXFP1DHODH | |
| SCHEMBL18355490 | 0.92 | MLYCD (0.37) | MLYCDRXFP1DHODH | |
| SCHEMBL18354685 | 0.90 | MLYCD (0.38) | MLYCDRXFP1DHODHHDAC8GFER | |
| SCHEMBL22332376 | 0.89 | MLYCD (0.39) | MLYCDRXFP1DHODHLRRK2GFER | |
| SCHEMBL18355928 | 0.89 | MLYCD (0.35) | MLYCDRXFP1DHODH | |
| SCHEMBL18354530 | 0.89 | HTT (0.34) | DHODHHDAC8 | |
| SCHEMBL18354398 | 0.89 | MLYCD (0.39) | MLYCDRXFP1DHODH | |
| SCHEMBL18354409 | 0.89 | DHODH (0.33) | RXFP1DHODHHDAC8 | |
| SCHEMBL18354645 | 0.89 | HDAC8 (0.34) | RXFP1DHODHHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9750246-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| US-9750246-B2 | Insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| US-20170000121-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
| US-20170000121-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170000121-A1 | INSECTICIDAL COMPOUNDS | ACHE, NIT2, CHRM1 | MLYCD 3166/4885RXFP1 1005/4885DHODH 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.