Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | COMT | P21964 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4562438 | 0.88 | RAB9A (0.42) | TOP1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL4561484 | 0.86 | MAPT (0.36) | TOP1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL4561428 | 0.86 | TOP1 (0.35) | TOP1RAB9AKMT2AMEN1MAPT | |
| SCHEMBL4562150 | 0.86 | KMT2A (0.40) | TOP1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL15336000 | 0.85 | TOP1 (0.33) | TOP1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL5944241 | 0.85 | PRKCQ (0.35) | TOP1KMT2AMEN1MAPTLMNA | |
| SCHEMBL4561387 | 0.84 | TOP1 (0.35) | TOP1RAB9AKMT2AMEN1NPC1 | |
| SCHEMBL17248230 | 0.82 | LMNA (0.42) | RAB9AKMT2AMEN1NPC1MAPT | |
| SCHEMBL10027563 | 0.81 | MEN1 (0.46) | RAB9AKMT2AMEN1COMTLMNA | |
| SCHEMBL4561407 | 0.81 | KDM4E (0.39) | RAB9AKMT2AMEN1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |