Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 14/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357972 | 0.91 | DDR1 (0.35) | DDR1EGLN1 | |
| SCHEMBL22280382 | 0.85 | SMN1; SMN2 (0.37) | DDR1EGLN1KDM4EALDH1A1HPGD | |
| SCHEMBL22349480 | 0.85 | CYP3A4 (0.32) | EGLN1CYP3A4 | |
| SCHEMBL22349432 | 0.84 | KDM4E (0.31) | KDM4EALDH1A1HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL18357976 | 0.84 | DDR1 (0.35) | DDR1 | |
| SCHEMBL20455829 | 0.83 | SMN1; SMN2 (0.35) | DDR1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| Lauroguadine SCHEMBL20545453 | 0.81 | S1PR1 (0.31) | — | |
| SCHEMBL18506244 | 0.80 | SMN1; SMN2 (0.35) | DDR1EGLN1KDM4EALDH1A1HPGD | |
| SCHEMBL31141512 | 0.80 | SMN1; SMN2 (0.35) | DDR1EGLN1KDM4EALDH1A1HPGD | |
| SCHEMBL18357977 | 0.77 | DDR1 (0.33) | DDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3317276-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2020-12-16 | — | — | EP | disclosed |
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-18 | — | — | US | disclosed |
| WO-2017001314-A1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, SQOR, ACHE | DDR1 4468/4885EGLN1 3453/4885KDM4E 3255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.