Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18357970 | 0.91 | DDR1 (0.34) | EGLN1 | |
| SCHEMBL18357558 | 0.85 | DDR1 (0.34) | CYP3A4EGLN1 | |
| SCHEMBL22349432 | 0.84 | KDM4E (0.31) | CYP3A4 | |
| SCHEMBL22291717 | 0.84 | DDR1 (0.32) | L3MBTL1IDH1 | |
| SCHEMBL18357996 | 0.81 | LMNA (0.36) | L3MBTL1IDH1 | |
| SCHEMBL18506251 | 0.79 | SMN1; SMN2 (0.33) | EGLN1L3MBTL1 | |
| SCHEMBL23811190 | 0.76 | DDR1 (0.30) | — | |
| SCHEMBL17494910 | 0.76 | DDR1 (0.32) | EGLN1 | |
| SCHEMBL18357972 | 0.76 | DDR1 (0.35) | EGLN1 | |
| SCHEMBL22291718 | 0.76 | DDR1 (0.34) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745396-B2 | Pesticidally active polycyclic derivatives with sulfur containing substituents | DDT, SQOR, ACHE | CYP3A4 171/4885EGLN1 3453/4885L3MBTL1 1417/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.