Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | MAX | P61244 | 1/20 | 0.36 |
| ▸ | ASPH | Q12797 | 1/20 | 0.35 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.35 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701941 | 0.71 | KDM4E (0.60) | KDM4EL3MBTL1TDP1ALOX15TSHR | |
| SCHEMBL12858096 | 0.71 | HCAR3 (0.36) | KDM4EL3MBTL1HCAR3TDP1ALOX15 | |
| SCHEMBL18358199 | 0.71 | NR4A2 (0.41) | TDP1MAPTIDO1 | |
| SCHEMBL31480604 | 0.70 | KDM4E (0.62) | KDM4EHCAR3TDP1ALOX15TSHR | |
| SCHEMBL25487645 | 0.70 | KDM4E (0.62) | KDM4EHCAR3TDP1ALOX15TSHR | |
| SCHEMBL23530075 | 0.70 | GABRP (0.62) | KDM4EL3MBTL1TDP1ALOX15TSHR | |
| SCHEMBL14919050 | 0.70 | KDM4E (0.58) | KDM4EL3MBTL1TDP1ALOX15TSHR | |
| SCHEMBL1424972 | 0.69 | KDM4E (0.49) | KDM4EL3MBTL1TDP1ALOX15TSHR | |
| SCHEMBL11894355 | 0.69 | KDM4E (0.67) | KDM4EL3MBTL1TDP1ALOX15TSHR | |
| SCHEMBL1425108 | 0.68 | KDM4E (0.56) | KDM4EL3MBTL1TDP1ALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017004608-A1 | OXADIAZOLE MODULATORS OF S1P METHODS OF MAKING AND USING | EXELIXIS, INC. (US) | 2017-01-05 | — | — | WO | disclosed |