Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.44 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ECE1 | P42892 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.39 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25487645 | 1.00 | KDM4E (0.62) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL15652792 | 0.84 | ALDH1A1 (0.47) | KDM4ELMNAALDH1A1HCAR3GRM5 | |
| SCHEMBL23964983 | 0.83 | ALDH1A1 (0.56) | KDM4ELMNAALDH1A1GRM5SMN1; SMN2 | |
| Potassium Ion SCHEMBL28087711 | 0.83 | ALDH1A1 (0.46) | KDM4ELMNAALDH1A1HCAR3GRM5 | |
| SCHEMBL3117402 | 0.79 | KDM4E (0.68) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL30951916 | 0.79 | KDM4E (0.68) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL16834707 | 0.78 | KDM4E (0.57) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL12541310 | 0.78 | TDP1 (0.44) | KDM4ELMNAALOX15TSHRTDP1 | |
| SCHEMBL22455532 | 0.76 | KDM4E (0.64) | KDM4ELMNAALOX15TSHRACMSD | |
| SCHEMBL19151675 | 0.76 | KDM4E (0.64) | KDM4ELMNAALOX15TSHRACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025054361-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2025-03-13 | — | — | WO | disclosed |