Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257763 | 0.85 | MEP1B (0.55) | MCL1KMT2ABRD4HTTACHE | |
| SCHEMBL15881204 | 0.81 | CA1 (0.50) | RXFP1MCL1MEN1KMT2ATSHR | |
| SCHEMBL30902183 | 0.81 | POLB (0.50) | BRD4LMNA | |
| SCHEMBL31349695 | 0.81 | ALDH1A1 (0.56) | MCL1MEN1KMT2AMAPK1BRD4 | |
| SCHEMBL11475986 | 0.81 | ALDH1A1 (0.56) | MCL1MEN1KMT2AMAPK1BRD4 | |
| SCHEMBL8023235 | 0.80 | MCL1 (0.51) | RXFP1MCL1MEN1KMT2ATSHR | |
| SCHEMBL427882 | 0.79 | RXFP1 (0.48) | RXFP1MCL1MEN1KMT2ATSHR | |
| SCHEMBL427881 | 0.79 | RXFP1 (0.48) | RXFP1MCL1MEN1KMT2ATSHR | |
| SCHEMBL1727450 | 0.79 | PDIA6 (0.51) | RXFP1MCL1MEN1KMT2ATSHR | |
| SCHEMBL29913439 | 0.79 | PDIA6 (0.51) | RXFP1MCL1MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2638014-B1 | N-SULFONYLATED TETRAHYDROQUINOLINES AND RELATED BICYCLIC COMPOUNDS FOR INHIBITION OF ROR-GAMMA ACTIVITY AND THE TREATMENT OF DISEASES | LYCERA CORP (US) | 2017-01-04 | — | — | EP | disclosed |