Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 4/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | PLD2 | O14939 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1833680 | 0.95 | OPRM1 (0.51) | OPRM1OPRL1OPRK1KDM4EALDH1A1 | |
| SCHEMBL1831375 | 0.90 | OPRM1 (0.52) | OPRM1OPRL1OPRK1KDM4EALDH1A1 | |
| SCHEMBL1839221 | 0.90 | OPRM1 (0.53) | CYP3A4OPRM1OPRL1OPRK1KDM4E | |
| SCHEMBL1836588 | 0.90 | OPRM1 (0.51) | CYP3A4OPRM1OPRL1OPRK1KDM4E | |
| SCHEMBL1836056 | 0.89 | OPRM1 (0.55) | OPRM1OPRL1OPRK1ALDH1A1BCHE | |
| SCHEMBL1835996 | 0.88 | OPRM1 (0.54) | CYP3A4OPRM1OPRL1OPRK1KDM4E | |
| SCHEMBL1832410 | 0.88 | HSD11B1 (0.45) | OPRM1OPRL1OPRK1KDM4EALDH1A1 | |
| SCHEMBL1835696 | 0.88 | OPRM1 (0.41) | OPRM1OPRL1OPRK1KDM4EALDH1A1 | |
| SCHEMBL1833973 | 0.88 | OPRM1 (0.46) | OPRM1OPRL1OPRK1KDM4EALDH1A1 | |
| SCHEMBL1832067 | 0.87 | OPRM1 (0.45) | OPRM1OPRL1OPRK1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160098-B9 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2011-05-18 | — | — | EP | claimed |
| EP-2160098-B1 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-11-10 | — | — | EP | claimed |