SCHEMBL18360202

SCHEMBL18360202

CNC(=O)[C@H](COC(=O)CNC(=O)OC(C)(C)C)NC(=O)OC(C)(C)C

nearest known ligand 0.45

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CTSS P25774 13/20 0.45
CTSK P43235 11/20 0.45
CTSL P07711 3/20 0.43
CTSB P07858 2/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
HTT P42858 1/20 0.42
CAPN1 P07384 1/20 0.38
PPARA Q07869 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18360201 0.84 CYP1A2 (0.43) CTSSCTSKCTSLCTSBCYP1A2
SCHEMBL1867256 0.84 CTSS (0.44) CTSSCTSKCTSLCTSBCYP1A2
SCHEMBL18360422 0.83 CYP1A2 (0.58) CTSSCTSKCTSLCTSBCYP1A2
SCHEMBL18360368 0.82 CYP1A2 (0.41) CTSSCTSKCTSLCTSBCYP1A2
SCHEMBL21012901 0.81 CTSK (0.49) CTSSCTSKCTSLCTSBCYP1A2
SCHEMBL13936599 0.80 CTSK (0.47) CTSSCTSKCTSLCTSBCYP1A2
SCHEMBL18360336 0.79 CTSS (0.57) CTSSCTSKCTSLCTSBPPARA
SCHEMBL18295821 0.79 CA1 (0.45) CTSSCTSKCTSLCTSBCYP1A2
SCHEMBL6240594 0.77 CYP1A2 (0.51) CTSSCTSKCTSLCTSBCYP1A2
SCHEMBL24815320 0.77 CTSK (0.65) CTSSCTSKCTSLCTSBCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10919840-B2 Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials SEIKAGAKU CORPORATION (JP) 2021-02-16 US disclosed
EP-3101064-B1 DIAMINE CROSSLINKING AGENT, ACIDIC POLYSACCHARIDE CROSSLINKED BODY, AND MEDICAL MATERIAL SEIKAGAKU KOGYO CO LTD (JP) 2020-07-15 EP disclosed
US-20190345312-A1 DIAMINE CROSSLINKING AGENTS, CROSSLINKED ACIDIC POLYSACCHARIDES AND MEDICAL MATERIALS SEIKAGAKU CORPORATION (JP) 2019-11-14 US disclosed
US-10294195-B2 Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials SEIKAGAKU CORPORATION (JP) 2019-05-21 US disclosed
US-20170001948-A1 DIAMINE CROSSLINKING AGENTS, CROSSLINKED ACIDIC POLYSACCHARIDES AND MEDICAL MATERIALS SEIKAGAKU CORPORATION (JP) 2017-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10294195-B2 Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials SAT1, ACMSD, ADM2 CTSS 4147/4885CTSK 4211/4885CTSL 4159/4885
US-20170001948-A1 DIAMINE CROSSLINKING AGENTS, CROSSLINKED ACIDIC POLYSACCHARIDES AND MEDICAL MATERIALS SAT1, ACMSD, ADM2 CTSS 4147/4885CTSK 4211/4885CTSL 4159/4885
US-10919840-B2 Diamine crosslinking agents, crosslinked acidic polysaccharides and medical materials SAT1, ACMSD, ADM2 CTSS 4147/4885CTSK 4211/4885CTSL 4159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.