Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | HSD17B13 | Q7Z5P4 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18360520 | 0.90 | HSD17B13 (0.49) | ROCK2BRD4CREBBPHSD17B13EPHX2 | |
| SCHEMBL18360506 | 0.87 | ROCK2 (0.56) | ROCK2HSD17B13EPHX2ROCK1PPARG | |
| SCHEMBL18360523 | 0.86 | HPGD (0.48) | ROCK2CA12CA1CA2CA9 | |
| SCHEMBL18354779 | 0.85 | PTGES (0.47) | ROCK2EPHX2CA12CA1CA2 | |
| SCHEMBL18360483 | 0.80 | CA1 (0.60) | PPARGCA12CA1CA2CA9 | |
| SCHEMBL18360474 | 0.77 | HPGD (0.48) | ROCK2PPARGCA12CA1CA2 | |
| SCHEMBL18360471 | 0.77 | PDE4A (0.52) | ROCK2ROCK1CA12CA1CA2 | |
| SCHEMBL18360407 | 0.76 | CA1 (0.62) | CA1CA2 | |
| SCHEMBL18354519 | 0.75 | PTGES (0.47) | ROCK2HSD17B13EPHX2PPARGCA12 | |
| SCHEMBL18360531 | 0.75 | CA1 (0.41) | CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170000133-A1 | BENZOXABOROLE FUNGICIDES | SYNGENTA PARTICIPATIONS AG (SE) | 2017-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170000133-A1 | BENZOXABOROLE FUNGICIDES | CYP4X1, BROX, CYP1B1 | ROCK2 3780/4885BRD4 1635/4885CREBBP 2888/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.