SCHEMBL1836166

SCHEMBL1836166

C=C(C(=O)O)C(F)(F)C(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18979301 1.00 THRB (0.38) THRB
SCHEMBL82681 0.80 THRB (0.48) THRB
SCHEMBL4301155 0.78 THRB (0.44) THRB
SCHEMBL6440412 0.76 ALDH1A1 (0.32)
SCHEMBL5165627 0.74 TET2 (0.43) THRB
SCHEMBL1594710 0.74 TET2 (0.43) THRB
SCHEMBL11146351 0.73 THRB (0.40) THRB
SCHEMBL688532 0.73 THRB (0.40) THRB
SCHEMBL10662916 0.71 KDM4E (0.34)
SCHEMBL23522592 0.71 THRB (0.58) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230340855-A1 PRESSURE COLLAPSIBLE CLOSED CELLULAR SWELL PACKER HALLIBURTON ENERGY SERVICES, INC. 2023-10-26 US disclosed
US-20170138149-A1 GAS RESPONSIVE MATERIAL FOR SWELLABLE PACKERS HALLIBURTON ENERGY SERVICES, INC. 2017-05-18 US disclosed
WO-2016187426-A1 A DEVICE THAT DELIVERS A SUSTAINED LOW-DOSE OF A MYOPIA-SUPPRESSING DRUG AMORPHEX THERAPEUTICS LLC (US) 2016-11-24 WO disclosed
WO-2016022093-A1 GAS RESPONSIVE MATERIAL FOR SWELLABLE PACKERS HALLIBURTON ENERGY SERVICES, INC. (US) 2016-02-11 WO disclosed
EP-2054452-B1 POLY(METH)ACRYLAMIDES AND POLY(METH)ACRYLATES CONTAINING FLUORINATED AMIDE DU PONT (US) 2012-09-19 EP disclosed
EP-1856169-B1 MOULDING COMPOSITION FOR PREPARATION OF PRECISION OPTICS NANOGATE IND SOLUTIONS GMBH (DE) 2011-05-11 EP disclosed