Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.43 |
| ▸ | MLNR | O43193 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835262 | 0.95 | CHRM1 (0.44) | CHRM2CHRM1OPRM1OPRK1PMP22 | |
| SCHEMBL1834990 | 0.92 | OPRM1 (0.46) | CHRM2CHRM1OPRM1OPRK1CYP2D6 | |
| SCHEMBL1838782 | 0.90 | OPRM1 (0.48) | CHRM2CHRM1OPRM1OPRK1DRD2 | |
| SCHEMBL1841561 | 0.90 | ALDH1A1 (0.44) | CHRM2CHRM1OPRM1OPRK1CYP2D6 | |
| SCHEMBL3403282 | 0.89 | OPRM1 (0.40) | CHRM2CHRM1OPRM1OPRK1PMP22 | |
| SCHEMBL1834569 | 0.88 | CYP3A4 (0.41) | CHRM2CHRM1OPRM1OPRK1PMP22 | |
| SCHEMBL1835180 | 0.88 | CHRM2 (0.39) | CHRM2CHRM1OPRM1OPRK1PMP22 | |
| SCHEMBL1835799 | 0.88 | OPRM1 (0.47) | CHRM2CHRM1OPRM1OPRK1CYP2D6 | |
| SCHEMBL1837577 | 0.88 | CHRM2 (0.39) | CHRM2CHRM1OPRM1OPRK1PMP22 | |
| SCHEMBL1831699 | 0.88 | ALDH1A1 (0.41) | CHRM2CHRM1OPRM1OPRK1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160098-B9 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2011-05-18 | — | — | EP | claimed |
| EP-2160098-B1 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-11-10 | — | — | EP | claimed |