Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 7/20 | 0.48 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.43 |
| ▸ | PLD2 | O14939 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1835262 | 0.93 | CHRM1 (0.44) | OPRM1CALCRLBCHEACHEHSD11B1 | |
| SCHEMBL1835016 | 0.93 | OPRM1 (0.50) | OPRM1CALCRLBCHEACHEHSD11B1 | |
| SCHEMBL1834990 | 0.90 | OPRM1 (0.46) | OPRM1CALCRLBCHEACHEPAX8 | |
| SCHEMBL1836256 | 0.90 | CHRM2 (0.43) | OPRM1CALCRLBCHEACHEHSD11B1 | |
| SCHEMBL1841561 | 0.88 | ALDH1A1 (0.44) | OPRM1CALCRLBCHEACHEHSD11B1 | |
| SCHEMBL1833772 | 0.88 | OPRM1 (0.44) | OPRM1CALCRLBCHEACHEHSD11B1 | |
| SCHEMBL3403282 | 0.88 | OPRM1 (0.40) | OPRM1CALCRLBCHEACHEPAX8 | |
| SCHEMBL1834960 | 0.87 | OPRM1 (0.41) | OPRM1CALCRLBCHEACHEHSD11B1 | |
| SCHEMBL1835799 | 0.87 | OPRM1 (0.47) | OPRM1CALCRLHSD11B1PAX8ALDH1A1 | |
| SCHEMBL1834569 | 0.87 | CYP3A4 (0.41) | OPRM1CALCRLBCHEACHEPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160098-B9 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2011-05-18 | — | — | EP | claimed |
| EP-2160098-B1 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-11-10 | — | — | EP | claimed |