Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 10/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18364190 | 0.86 | ZDHHC2 (0.50) | MTNR1AMTNR1BL3MBTL1ZDHHC2HCAR2 | |
| SCHEMBL18374811 | 0.85 | ZDHHC2 (0.49) | MTNR1AMTNR1BL3MBTL1ZDHHC2HSD17B10 | |
| SCHEMBL18352553 | 0.85 | ZDHHC2 (0.48) | MTNR1AMTNR1BZDHHC2HSD17B10HCAR2 | |
| SCHEMBL18364193 | 0.85 | ZDHHC2 (0.52) | MTNR1AMTNR1BL3MBTL1ZDHHC2HCAR2 | |
| SCHEMBL18364207 | 0.85 | ZDHHC2 (0.49) | MTNR1AMTNR1BL3MBTL1ZDHHC2HCAR2 | |
| SCHEMBL18354871 | 0.83 | TAAR1 (0.50) | MTNR1AMTNR1BZDHHC2HSD17B10HCAR2 | |
| SCHEMBL18364192 | 0.82 | ZDHHC2 (0.47) | MTNR1AMTNR1BL3MBTL1ZDHHC2TSHR | |
| SCHEMBL18364198 | 0.82 | RAB9A (0.51) | MTNR1AMTNR1BL3MBTL1ZDHHC2HCAR2 | |
| SCHEMBL18364208 | 0.82 | ZDHHC2 (0.50) | MTNR1AMTNR1BL3MBTL1ZDHHC2ALOX15 | |
| SCHEMBL18412214 | 0.82 | ATM (0.48) | MTNR1AMTNR1BL3MBTL1USP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008835-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | Nguyen, Mark Quang (US) | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008835-A1 | FUMARATE COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THEREOF, AND METHODS OF USE | FH, FPGS, APC | MTNR1A 3360/4885MTNR1B 2855/4885L3MBTL1 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.