Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17040253 | 0.87 | PTPN1 (0.50) | PTPN1CYP1A2NR4A2 | |
| Hydrochloric Acid SCHEMBL11596232 | 0.84 | PTPN1 (0.48) | PTPN1CYP1A2NR4A2 | |
| SCHEMBL185561 | 0.75 | — | — | |
| SCHEMBL14112944 | 0.73 | — | — | |
| SCHEMBL22436525 | 0.73 | PTPN1 (0.41) | PTPN1 | |
| Hydrochloric Acid SCHEMBL22436543 | 0.73 | PTPN1 (0.41) | PTPN1 | |
| Potassium SCHEMBL834916 | 0.73 | PTPN1 (0.41) | PTPN1 | |
| SCHEMBL13758485 | 0.71 | MAPT (0.42) | CYP1A2 | |
| SCHEMBL8334992 | 0.70 | — | — | |
| SCHEMBL8840142 | 0.70 | PTPN1 (0.39) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | HAO2, ASF1A, FTO | PTPN1 4354/4885CYP1A2 2176/4885NR4A2 3658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.