Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8191180 | 0.91 | MAPT (0.55) | MAPTKMT2AMEN1NPC1POLB | |
| SCHEMBL22972761 | 0.89 | TSHR (0.67) | TP53TSHRKMT2AMEN1NPC1 | |
| SCHEMBL2029621 | 0.89 | TSHR (0.67) | TP53TSHRKMT2AMEN1NPC1 | |
| SCHEMBL17040204 | 0.89 | TSHR (0.67) | TP53TSHRKMT2AMEN1NPC1 | |
| SCHEMBL7050772 | 0.87 | MAPT (0.59) | TSHRMAPTKMT2AMEN1NPC1 | |
| SCHEMBL29895062 | 0.87 | MAPT (0.59) | TSHRMAPTKMT2AMEN1NPC1 | |
| SCHEMBL211540 | 0.86 | TSHR (0.71) | TP53TSHRMAPTKMT2ARAB9A | |
| Potassium SCHEMBL31268570 | 0.84 | TSHR (0.67) | TP53TSHRMAPTKMT2ARAB9A | |
| Barium SCHEMBL31268595 | 0.84 | TSHR (0.67) | TP53TSHRMAPTKMT2ARAB9A | |
| Calcium SCHEMBL31268578 | 0.84 | TSHR (0.67) | TP53TSHRMAPTKMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170081345-A1 | METAL-ORGANIC FRAMEWORKS CHARACTERIZED BY HAVING A LARGE NUMBER OF ADSORPTION SITES PER UNIT VOLUME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-03-23 | — | — | US | disclosed |
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081345-A1 | METAL-ORGANIC FRAMEWORKS CHARACTERIZED BY HAVING A LARGE NUMBER OF ADSORPTION SITES PER UNIT VOLUME | EPCAM, SOD1, ABCB7 | TP53 688/4885TSHR 3869/4885MAPT 1394/4885 |
| US-20170008915-A1 | ACID, SOLVENT, AND THERMAL RESISTANT METAL-ORGANIC FRAMEWORKS | HAO2, ASF1A, FTO | TP53 1115/4885TSHR 4648/4885MAPT 2232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.