SCHEMBL18364645

SCHEMBL18364645

CC(c1ccccc1)c1c[nH]c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.62
FFAR1 O14842 2/20 0.62
SRC P12931 1/20 0.58
HTR2A P28223 1/20 0.57
HTR2C P28335 1/20 0.57
HTR2B P41595 1/20 0.57
NR3C1 P04150 1/20 0.56
PGR P06401 1/20 0.56
NR3C2 P08235 1/20 0.56
AR P10275 1/20 0.56
CYP2D6 P10635 1/20 0.56
SLC6A2 P23975 1/20 0.56
SLC6A4 P31645 1/20 0.56
KCNH2 Q12809 1/20 0.56
MAPT P10636 3/20 0.53
MGAM O43451 3/20 0.51
GAA P10253 3/20 0.51
SI P14410 3/20 0.51
MGAM2 Q2M2H8 3/20 0.51
NOD2 Q9HC29 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18364660 0.90 GPR84 (0.56) GPR84FFAR1SRCHTR2AHTR2C
Vibrindole A SCHEMBL5960513 0.88 GPR84 (0.71) GPR84FFAR1SRCHTR2AHTR2C
SCHEMBL15161623 0.86 GPR84 (0.51) GPR84FFAR1SRCHTR2AHTR2C
SCHEMBL22643880 0.82 HTR1D (0.49) GPR84FFAR1SRCHTR2AHTR2C
SCHEMBL27946627 0.81 SRC (0.53) GPR84FFAR1SRCHTR2AHTR2C
SCHEMBL30040360 0.81 MAPT (0.69) GPR84FFAR1SRCHTR2AHTR2C
SCHEMBL10717194 0.81 NR3C1 (0.73) GPR84FFAR1SRCHTR2AHTR2C
SCHEMBL3343111 0.81 MAPT (0.69) GPR84FFAR1SRCHTR2AHTR2C
SCHEMBL31744723 0.80 HTR2A (0.48) GPR84FFAR1SRCHTR2AHTR2C
SCHEMBL30626309 0.80 GPR84 (0.71) GPR84FFAR1SRCHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9783561-B2 Chiral imidodiphosphates and derivatives thereof STUDIENGESELLSCHAFT KOHLE MBH (DE) 2017-10-10 US disclosed
US-20170008843-A1 MONOMER, ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2017-01-12 US disclosed
CN-103333097-A Synthesis method of diindolylmethane derivatives UNIV CHONGQING 2013-10-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008843-A1 MONOMER, ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS MSMO1, NOM1, CD68 GPR84 2980/4885FFAR1 3685/4885SRC 1429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.