Sugi Predict

Sugi Predict / Compounds / SCHEMBL3343111

SCHEMBL3343111

SCHEMBL3343111

c1ccc(C(c2c[nH]c3ccccc23)c2c[nH]c3ccccc23)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.69
▸ NR3C1 P04150 1/20 0.69
▸ PGR P06401 1/20 0.69
▸ NR3C2 P08235 1/20 0.69
▸ AR P10275 1/20 0.69
▸ GPR84 Q9NQS5 3/20 0.59
▸ MEN1 O00255 3/20 0.57
▸ KMT2A Q03164 3/20 0.57
▸ SRC P12931 1/20 0.57
▸ FFAR1 O14842 2/20 0.56
▸ CYP2D6 P10635 1/20 0.55
▸ SLC6A2 P23975 1/20 0.55
▸ SLC6A4 P31645 1/20 0.55
▸ KCNH2 Q12809 1/20 0.55
▸ MGAM O43451 3/20 0.55
▸ GAA P10253 3/20 0.55
▸ SI P14410 3/20 0.55
▸ MGAM2 Q2M2H8 3/20 0.55
▸ HDAC3 O15379 1/20 0.55
▸ HDAC4 P56524 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30040360 1.00 MAPT (0.69) MAPTNR3C1PGRNR3C2AR
SCHEMBL10717194 0.96 NR3C1 (0.73) MAPTNR3C1PGRNR3C2AR
SCHEMBL3344603 0.89 NR3C1 (0.61) MAPTNR3C1PGRNR3C2AR
SCHEMBL24145348 0.89 MAPT (0.58) MAPTNR3C1PGRNR3C2AR
SCHEMBL8592636 0.87 MAPT (0.65) MAPTNR3C1PGRNR3C2AR
SCHEMBL29885627 0.87 MAPT (0.65) MAPTNR3C1PGRNR3C2AR
SCHEMBL3495495 0.85 GUSB (0.61) MAPTNR3C1PGRNR3C2AR
SCHEMBL7290548 0.85 MAPT (0.59) MAPTNR3C1PGRNR3C2AR
SCHEMBL3493768 0.85 NR3C1 (0.61) MAPTNR3C1PGRNR3C2AR
SCHEMBL31511311 0.85 NR3C1 (0.57) MAPTNR3C1PGRNR3C2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230111140-A1 TREATMENT OF PAIN BY TARGETING NR4A1 UNIV CINCINNATI (US) 2023-04-13 — — US claimed
US-20100087504-A1 Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2010-04-08 — — US claimed
US-12285407-B2 Bis-indolylmethane derivatives and uses thereof THE UNIVERSITY OF THE WEST INDIES (TT) 2025-04-29 — — US disclosed
US-20230111140-A1 TREATMENT OF PAIN BY TARGETING NR4A1 UNIV CINCINNATI (US) 2023-04-13 — — US disclosed
US-20230111140-A1 TREATMENT OF PAIN BY TARGETING NR4A1 UNIV CINCINNATI (US) 2023-04-13 — — US disclosed
US-20230113363-A1 METHODS FOR TREATING ENDOMETRIOSIS THE TEXAS A&M UNIVERSITY SYSTEM (US) 2023-04-13 — — US disclosed
EP-4103216-A1 TREATMENT OF PAIN BY TARGETING NR4A1 University of Cincinnati (US) 2022-12-21 — — EP disclosed
US-11421223-B2 Processes and host cells for genome, pathway, and biomolecular engineering ENEVOLV, INC. (US) 2022-08-23 — — US disclosed
US-20210401803-A1 COMPOUNDS AND USES THEREOF THE UNIVERSITY OF THE WEST INDIES (TT) 2021-12-30 — — US disclosed
US-20210401803-A1 COMPOUNDS AND USES THEREOF THE UNIVERSITY OF THE WEST INDIES (TT) 2021-12-30 — — US disclosed
EP-3883564-A1 COMPOUNDS AND USES THEREOF The University of the West Indies (TT) 2021-09-29 — — EP disclosed
WO-2010042657-A1 USE OF DIINDOLYLMETHANE (DIM) COMPOUNDS AND DERIVATIVES AS NEUROPROTECTIVE AGENTS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2010-04-15 — — WO disclosed
WO-2010042657-A1 USE OF DIINDOLYLMETHANE (DIM) COMPOUNDS AND DERIVATIVES AS NEUROPROTECTIVE AGENTS COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2010-04-15 — — WO disclosed
US-20100087504-A1 Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2010-04-08 — — US disclosed
US-20100087504-A1 Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2010-04-08 — — US disclosed
US-20100087504-A1 Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2010-04-08 — — US disclosed
CN-100412058-C Process for synthesizing bis-indolyl alkyl compounds UNIV SOOCHOW (CN) 2008-08-20 — — CN disclosed
CN-1332948-C Double indolyl derivative synthesizing process UNIV SUZHOU (CN) 2007-08-22 — — CN disclosed
CN-1706829-A Double indolyl derivative synthesizing process UNIV SUZHOU (CN) 2005-12-14 — — CN disclosed
CN-1699341-A Process for synthesizing bis-indolyl alkyl compounds UNIV SUZHOU (CN) 2005-11-23 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230113363-A1 METHODS FOR TREATING ENDOMETRIOSIS NR4A3, NR4A1, NR4A2 MAPT 4791/4885NR3C1 15/4885PGR 53/4885
US-20210401803-A1 COMPOUNDS AND USES THEREOF CFTR, FPR1, CFB MAPT 1966/4885NR3C1 4128/4885PGR 2557/4885
US-12285407-B2 Bis-indolylmethane derivatives and uses thereof IDO1, FHIT, IDO2 MAPT 338/4885NR3C1 3590/4885PGR 2228/4885
US-20100087504-A1 Use of Diindolylmethane (DIM) Compounds and Derivatives as Neuroprotective Agents AIFM1, NLN, SNCA MAPT 123/4885NR3C1 2043/4885PGR 3216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.