SCHEMBL18364663

SCHEMBL18364663

CC(c1ccccc1)c1ccc2[nH]c3ccccc3c2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 7/20 0.57
AHR P35869 1/20 0.52
KDM4E B2RXH2 3/20 0.49
ALDH1A1 P00352 2/20 0.49
HSD17B10 Q99714 2/20 0.49
KMT2A Q03164 2/20 0.49
MAPT P10636 2/20 0.49
MEN1 O00255 1/20 0.49
HPGD P15428 1/20 0.49
GPR3 P46089 1/20 0.48
GABRA1 P14867 3/20 0.45
GABRG2 P18507 3/20 0.45
GABRB3 P28472 3/20 0.45
GABRA5 P31644 3/20 0.45
GABRA3 P34903 3/20 0.45
GABRA2 P47869 3/20 0.45
GABRA4 P48169 3/20 0.45
GABRA6 Q16445 3/20 0.45
GABRP O00591 2/20 0.44
GABRD O14764 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10114707 0.87 MLKL (0.52) KIF11KDM4EALDH1A1HSD17B10KMT2A
SCHEMBL31549973 0.84 KIF11 (0.79) KIF11AHRKDM4EALDH1A1HSD17B10
SCHEMBL13010630 0.84 KIF11 (0.79) KIF11AHRKDM4EALDH1A1HSD17B10
SCHEMBL28201526 0.82 AHR (0.55) KIF11AHRKDM4EALDH1A1HSD17B10
SCHEMBL869228 0.81 KIF11 (0.59) KIF11AHRKDM4EALDH1A1HSD17B10
SCHEMBL18364664 0.81 CDK4 (0.51) KIF11AHRKDM4EALDH1A1HSD17B10
SCHEMBL10114722 0.80 BCHE (0.50) KIF11KDM4EALDH1A1HSD17B10KMT2A
SCHEMBL18364653 0.79 AHR (0.52) KIF11AHRKDM4EALDH1A1HSD17B10
SCHEMBL11067278 0.79 KMT2A (0.66) KIF11AHRKDM4EALDH1A1KMT2A
SCHEMBL28363827 0.78 AHR (0.59) KIF11AHRKDM4EALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210020846-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2021-01-21 US disclosed
US-20170008843-A1 MONOMER, ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2017-01-12 US disclosed
US-20170008843-A1 MONOMER, ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS SAMSUNG SDI CO., LTD. (KR) 2017-01-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170008843-A1 MONOMER, ORGANIC LAYER COMPOSITION, ORGANIC LAYER, AND METHOD OF FORMING PATTERNS MSMO1, NOM1, CD68 KIF11 2816/4885AHR 2513/4885KDM4E 3936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.