SCHEMBL10114722

SCHEMBL10114722

Cc1ccc2[nH]c3ccc(C(C)c4ccc(-c5ccccc5)cc4)cc3c2c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.50
KDM4E B2RXH2 5/20 0.48
HPGD P15428 5/20 0.48
HSD17B10 Q99714 3/20 0.48
NPC1 O15118 3/20 0.48
LMNA P02545 2/20 0.48
RAB9A P51151 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
TP53 P04637 1/20 0.48
MAPT P10636 1/20 0.48
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
ALDH1A1 P00352 3/20 0.46
GFER P55789 2/20 0.46
HTT P42858 1/20 0.46
MLKL Q8NB16 1/20 0.46
POLB P06746 1/20 0.45
PTGS2 P35354 2/20 0.43
KIF11 P52732 4/20 0.42
ACHE P22303 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10114707 0.92 MLKL (0.52) BCHEKDM4EHPGDHSD17B10NPC1
SCHEMBL19773152 0.82 BCHE (0.59) BCHEKDM4EHPGDHSD17B10NPC1
SCHEMBL10114705 0.81 ACHE (0.58) BCHEKDM4EHPGDHSD17B10NPC1
SCHEMBL18364663 0.80 KIF11 (0.57) KDM4EHPGDHSD17B10MAPTMEN1
SCHEMBL10114713 0.79 KDM4E (0.53) BCHEKDM4EHPGDHSD17B10NPC1
SCHEMBL10114729 0.79 MLKL (0.46) BCHEKDM4EHPGDHSD17B10NPC1
SCHEMBL28256205 0.78 KIF11 (0.56) KDM4EKIF11
SCHEMBL15002841 0.78 KIF11 (0.61) BCHEKDM4EHPGDHSD17B10NPC1
SCHEMBL10114678 0.78 KIF11 (0.45) KDM4EHPGDHSD17B10NPC1LMNA
SCHEMBL10114714 0.78 NPC1 (0.48) BCHEKDM4EHPGDHSD17B10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8722841-B2 Carbazole novolak resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-05-13 US disclosed
US-8674052-B2 Carbazole novolak resin NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-03-18 US disclosed
US-20130122710-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-05-16 US disclosed
US-20120077345-A1 CARBAZOLE NOVOLAK RESIN NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2012-03-29 US disclosed