Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455815 | 0.78 | LOXL2 (0.45) | LOXL2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9661135 | 0.77 | LOXL2 (0.47) | LOXL2HSD17B10 | |
| SCHEMBL502 | 0.76 | TSHR (0.52) | ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL8881644 | 0.76 | TSHR (0.52) | ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL5542341 | 0.75 | HRH1 (0.46) | LOXL2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1361794 | 0.75 | NAPRT (0.47) | CYP1A2CYP3A4CYP2D6CYP2C9CYP19A1 | |
| SCHEMBL3092949 | 0.74 | IDO1 (0.50) | ALDH1A1CYP2C19KDM4EKMT2A | |
| SCHEMBL7617607 | 0.74 | TSHR (0.50) | ALDH1A1CYP1A2CYP2C19KMT2A | |
| SCHEMBL5254429 | 0.74 | HRH1 (0.48) | LOXL2ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL95538 | 0.73 | IDO1 (0.52) | LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2831059-B1 | PROCESSES FOR PREPARING TUBULYSIN DERIVATIVES AND CONJUGATES THEREOF | ENDOCYTE INC (US) | 2017-11-29 | — | — | EP | claimed |
| EP-1493747-B1 | PROCESS FOR PRODUCING MODIFIED PEPTIDE | DAIICHI SANKYO CO LTD (JP) | 2012-12-19 | — | — | EP | claimed |
| US-RE43802-E1 | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE LLC (US) | 2012-11-13 | — | — | US | claimed |
| US-20120214994-A1 | (3-FLUORO-2-HYDROXY)PROPYL-FUNCTIONALIZED ARYL DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR THE DIAGNOSIS OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASES | FUTURECHEM CO., LTD. (KR) | 2012-08-23 | — | — | US | claimed |
| CN-102382124-A | Ceftizoxime alapivoxil synthesized from cephalosporin drug intermediate and preparation method thereof | UNIV ZHENGZHOU | 2012-03-21 | — | — | CN | claimed |
| US-RE42889-E1 | α- and β- amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE LLC (US) | 2011-11-01 | — | — | US | claimed |
| US-7829564-B2 | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE LLC (US) | 2010-11-09 | — | — | US | claimed |
| US-20090023664-A1 | ALPHA- AND BETA-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE LLC (US) | 2009-01-22 | — | — | US | claimed |
| CN-100357267-C | Use of 2, 4-diamino-3-hydroxycarboxylic acid derivatives as proteasome inhibitors | NOVARTIS AG (CH) | 2007-12-26 | — | — | CN | claimed |
| CN-101085765-A | Compound with proteasome inhibition function and its preparing method and application | UNIV BEIJING (CN) | 2007-12-12 | — | — | CN | claimed |
| EP-0218099-B1 | AMIDES OF TEICOPLANIN COMPOUNDS | GRUPPO LEPETIT S.p.A. (IT) | 1991-12-11 | — | — | EP | claimed |
| US-5011940-A | Process for the preparation of bicyclic amino carboxylic acids, intermediates in this process, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | claimed |
| EP-0370283-A2 | Process for preparing 63-carboxyamides of teicoplanin antibiotics | GRUPPO LEPETIT S.p.A. (IT) | 1990-05-30 | — | — | EP | claimed |
| EP-0340245-A1 | SUBSTITUTED ALKYLAMIDES OF TEICOPLANIN COMPOUNDS. | LEPETIT SPA (IT) | 1989-11-08 | — | — | EP | claimed |
| US-4857520-A | Fused azepinone and azocinone derivatives, processes for their preparation, agents containing them and their use, and intermediates in their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-08-15 | — | — | US | claimed |
| WO-1988006600-A1 | SUBSTITUTED ALKYLAMIDES OF TEICOPLANIN COMPOUNDS | GRUPPO LEPETIT S.P.A. (IT) | 1988-09-07 | — | — | WO | claimed |
| CN-86106046-A | The acid amides of teicoplanin compounds | — | 1987-08-12 | — | — | CN | claimed |
| EP-0218099-A2 | Amides of teicoplanin compounds | GRUPPO LEPETIT S.p.A. (IT) | 1987-04-15 | — | — | EP | claimed |
| US-4185014-A | Kentenimine intermediates for 6α-methoxy-α-carboxy penicillins | BEECHAM GROUP LIMITED (GB) | 1980-01-22 | — | — | US | claimed |
| US-4098777-A | OLIGOPEPTIDES, TREATMENT OF AUTOIMMUNE DISEASES | MERCK & CO., INC. (US) | 1978-07-04 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023664-A1 | ALPHA- AND BETA-AMINO ACID HYDROXYETHYLAMINO SULFONAMIDES USEFUL AS RETROVIRAL PROTEASE INHIBITORS | DNPEP, ASPH, PREP | LOXL2 3809/4885ALDH1A1 1555/4885CYP1A2 3715/4885 |
| US-20120214994-A1 | (3-FLUORO-2-HYDROXY)PROPYL-FUNCTIONALIZED ARYL DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR THE DIAGNOSIS OR TREATMENT OF NEURODEGENERATIVE BRAIN DISEASES | APP, FABP7, SLC3A2 | LOXL2 3024/4885ALDH1A1 2595/4885CYP1A2 2662/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.