Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502 | 0.98 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL8881644 | 0.98 | TSHR (0.52) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL27597789 | 0.93 | TSHR (0.48) | TSHRIDO1AGXTALDH1A1CA1 | |
| Cyanide SCHEMBL27392144 | 0.91 | TSHR (0.46) | TSHRIDO1AGXTALDH1A1CA1 | |
| Methylene Chloride SCHEMBL28121276 | 0.91 | TSHR (0.46) | TSHRIDO1AGXTALDH1A1CA1 | |
| Methyl Alcohol SCHEMBL28296456 | 0.91 | ALDH1A1 (0.50) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL131471 | 0.85 | IDO1 (0.55) | TSHRIDO1AGXTLMNAPTGS1 | |
| SCHEMBL5545390 | 0.84 | LMNA (0.58) | CA1CA2CA9L3MBTL1SLC6A2 | |
| Phthalazine SCHEMBL29114773 | 0.82 | TSHR (0.39) | TSHRIDO1AGXTALDH1A1CA1 | |
| SCHEMBL11307829 | 0.82 | ALOX15 (0.45) | TSHRIDO1AGXTALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109662961-A | For improving the method and composition of cognitive function | 约翰斯霍普金斯大学 | 2019-04-23 | — | — | CN | disclosed |
| CN-109662964-A | For improving the method and composition of cognitive function | 约翰斯.霍普金斯大学 | 2019-04-23 | — | — | CN | disclosed |
| CN-107243007-A | Improve the method and composition of cognitive function | 约翰斯.霍普金斯大学 | 2017-10-13 | — | — | CN | disclosed |
| EP-1192465-A1 | DETECTION USING DENDRIMERS BEARING LABELS AND PROBES | DAKO A/S (DK) | 2002-04-03 | — | — | EP | disclosed |
| WO-2001002861-A1 | DETECTION USING DENDRIMERS BEARING LABELS AND PROBES | DAKO A/S (DK) | 2001-01-11 | — | — | WO | disclosed |