SCHEMBL18375111

SCHEMBL18375111

CCC[C@@H](C)C(=O)N[C@@H](C)C(=O)OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CTSK P43235 3/20 0.51
KDM4E B2RXH2 1/20 0.49
ATM Q13315 1/20 0.47
POLB P06746 1/20 0.47
CTSL P07711 1/20 0.46
CTSS P25774 1/20 0.46
CTSB P07858 1/20 0.46
TSHR P16473 1/20 0.46
METAP2 P50579 1/20 0.46
ACE P12821 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23651590 0.86 ALDH1A1 (0.60) CTSKATMCTSBACE
SCHEMBL11412502 0.85 ALDH1A1 (0.45) CTSKKDM4EATMCTSBTSHR
SCHEMBL12191588 0.84 CTSK (0.55) CTSKCTSLCTSSCTSB
SCHEMBL18803817 0.84 POLB (0.44) ATMPOLBCTSBMETAP2ACE
SCHEMBL20445581 0.84 ALDH1A1 (0.55) CTSKKDM4EATMPOLBCTSL
Hydrochloric Acid SCHEMBL5154116 0.83 ATM (0.47) CTSKATMCTSBMETAP2ACE
SCHEMBL11409558 0.82 ABCB1 (0.47) CTSKATMCTSBACE
SCHEMBL10773324 0.81 CTRB1 (0.54) CTSKATMCTSBMETAP2ACE
SCHEMBL9554893 0.81 ATM (0.53) CTSKATMCTSBACE
SCHEMBL29451987 0.81 CTRB1 (0.54) CTSKATMCTSBMETAP2ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017005879-A1 NITROXIDES FOR USE AS CONTRAST AGENTS FOR OVERHAUSER MAGNETIC RESONANCE IMAGING (OMRI) UNIVERSITE D'AIX MARSEILLE (FR) 2017-01-12 WO disclosed