SCHEMBL18375253

SCHEMBL18375253

Cc1cc(O)cc(C)c1C[C@H](NCl)C(N)=O

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 7/20 0.46
OPRD1 P41143 6/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8301882 0.78 OPRM1 (0.39) OPRM1OPRD1
SCHEMBL13282134 0.78 OPRM1 (0.39) OPRM1OPRD1
SCHEMBL19891259 0.77 OPRM1 (0.47) OPRM1OPRD1
SCHEMBL21890005 0.77 OPRM1 (0.47) OPRM1OPRD1
SCHEMBL24305550 0.77 OPRM1 (0.48) OPRM1OPRD1
SCHEMBL24305567 0.76 OPRM1 (0.43) OPRM1OPRD1
SCHEMBL6304792 0.75 OPRK1 (0.39) OPRM1OPRD1
SCHEMBL38802 0.75 OPRK1 (0.39) OPRM1OPRD1
SCHEMBL18072580 0.74 TACR1 (0.49) OPRM1OPRD1
SCHEMBL20369496 0.73 OPRM1 (0.41) OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017007695-A1 MU OPIOID RECEPTOR MODULATORS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2017-01-12 WO disclosed