Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38802 | 1.00 | OPRK1 (0.39) | OPRK1CYP3A4ACHEOPRM1OPRD1 | |
| SCHEMBL8301882 | 0.86 | OPRM1 (0.39) | OPRK1CYP3A4ACHEOPRM1OPRD1 | |
| SCHEMBL13282134 | 0.86 | OPRM1 (0.39) | OPRK1CYP3A4ACHEOPRM1OPRD1 | |
| SCHEMBL28168377 | 0.85 | OPRM1 (0.38) | CYP3A4ACHEOPRM1OPRD1 | |
| SCHEMBL18655444 | 0.83 | LMNA (0.45) | — | |
| SCHEMBL13288278 | 0.82 | OPRM1 (0.43) | OPRK1OPRM1OPRD1 | |
| SCHEMBL10636928 | 0.82 | CYP3A4 (0.41) | CYP3A4 | |
| SCHEMBL10636921 | 0.82 | CYP3A4 (0.41) | CYP3A4 | |
| SCHEMBL28168381 | 0.82 | OPRM1 (0.37) | OPRK1OPRM1OPRD1 | |
| SCHEMBL38327 | 0.81 | L3MBTL1 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016187537-A1 | MULTIFUNCTIONAL OPIOID RECEPTOR LIGANDS AND METHODS OF TREATING PAIN | THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2016-11-24 | — | — | WO | disclosed |
| US-6916905-B2 | Dmt-Tic di-and tri-peptidic derivatives and related compositions and methods of use | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2005-07-12 | — | — | US | disclosed |
| US-6753317-B1 | ANTAGONISTS FOR DELTA -OPIOID RECEPTORS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2004-06-22 | — | — | US | disclosed |
| WO-2003062261-A2 | DMT-TIC DI- AND TRI-PEPTIDIC DERIVATIVES AND RELATED COMPOSITIONS AND METHODS OF USE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-07-31 | — | — | WO | disclosed |
| US-20020161189-A1 | Dmt-Tic di-and tri-peptidic derivatives and related compositions and methods of use | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVIC | 2002-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020161189-A1 | Dmt-Tic di-and tri-peptidic derivatives and related compositions and methods of use | NMT2, TPST2, TEKT1 | OPRK1 2078/4885CYP3A4 2130/4885ACHE 4566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.