Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 3/20 | 0.58 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 5/20 | 0.53 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.53 |
| ▸ | JAK3 | P52333 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | TTK | P33981 | 3/20 | 0.49 |
| ▸ | JAK1 | P23458 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | CDK4 | P11802 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29370825 | 0.93 | FGFR2 (0.51) | FGFR2FGFR1KDRJAK2PTK2 | |
| SCHEMBL18376603 | 0.93 | FGFR2 (0.51) | FGFR2FGFR1KDRJAK2PTK2 | |
| SCHEMBL18377065 | 0.91 | PTK2 (0.55) | FGFR2FGFR1KDRJAK2PTK2 | |
| SCHEMBL29368482 | 0.91 | PTK2 (0.55) | FGFR2FGFR1KDRJAK2PTK2 | |
| SCHEMBL18376246 | 0.90 | JAK2 (0.56) | FGFR1KDRJAK2PTK2JAK3 | |
| SCHEMBL29371334 | 0.90 | JAK2 (0.56) | FGFR1KDRJAK2PTK2JAK3 | |
| SCHEMBL18376604 | 0.90 | FGFR2 (0.48) | FGFR2FGFR1KDRJAK2PTK2 | |
| SCHEMBL29370862 | 0.90 | FGFR2 (0.48) | FGFR2FGFR1KDRJAK2PTK2 | |
| SCHEMBL18376662 | 0.89 | TTK (0.51) | FGFR2FGFR1KDRJAK2JAK3 | |
| SCHEMBL18376597 | 0.89 | TTK (0.50) | FGFR2FGFR1KDRJAK2PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017005137-A1 | QUINAZOLINE COMPOUND, INTERMEDIATE, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USES THEREOF | 吉林大学 | 2017-01-12 | — | — | WO | disclosed |