Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11158758 | 1.00 | SMN1; SMN2 (0.56) | SMN1; SMN2NPC1RAB9ALMNAUSP2 | |
| SCHEMBL15955454 | 0.98 | SMN1; SMN2 (0.55) | SMN1; SMN2NPC1RAB9ALMNAUSP2 | |
| SCHEMBL10512429 | 0.93 | LMNA (0.52) | SMN1; SMN2NPC1RAB9ALMNAUSP2 | |
| SCHEMBL14904507 | 0.88 | SMN1; SMN2 (0.57) | SMN1; SMN2NPC1RAB9ALMNAUSP2 | |
| SCHEMBL10511898 | 0.86 | LMNA (0.55) | SMN1; SMN2NPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL15016680 | 0.83 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9ALMNAASAH1 | |
| SCHEMBL12519824 | 0.81 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ALMNAUSP2 | |
| SCHEMBL9545874 | 0.79 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ALMNAASAH1 | |
| SCHEMBL9468671 | 0.79 | NPC1 (0.43) | SMN1; SMN2NPC1RAB9ALMNAASAH1 | |
| SCHEMBL10988576 | 0.79 | NPC1 (0.52) | SMN1; SMN2NPC1RAB9ALMNAASAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170009062-A1 | DISPERSION CONTAINING METAL OXIDE PARTICLES | NIPPON SHOKUBAI CO., LTD. (JP) | 2017-01-12 | — | — | US | disclosed |