Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15955454 | 0.90 | SMN1; SMN2 (0.55) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL18377331 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL11158758 | 0.88 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL10512429 | 0.88 | LMNA (0.52) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL10512588 | 0.87 | LMNA (0.59) | SMN1; SMN2ALDH1A1LMNAKDM4EL3MBTL1 | |
| SCHEMBL10511898 | 0.84 | LMNA (0.55) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL16800096 | 0.81 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1RAB9ANPC1KDM4E | |
| SCHEMBL18530454 | 0.80 | LMNA (0.43) | SMN1; SMN2ALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL14865536 | 0.79 | IDO1 (0.47) | LMNAMEN1KMT2A | |
| SCHEMBL4426990 | 0.79 | LMNA (0.56) | SMN1; SMN2LMNARAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9320685-B2 | Dental compositions comprising ethylenically unsaturated addition-fragmentation agent | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-04-26 | — | — | US | disclosed |
| US-9295617-B2 | Dental composition, method of producing and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2016-03-29 | — | — | US | disclosed |
| US-20150238389-A1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | SOLVENTUM INTELLECTUAL PROPERTIES COMPANY | 2015-08-27 | — | — | US | disclosed |
| US-9056043-B2 | Dental compositions comprising ethylenically unsaturated addition-fragmentation agent | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-06-16 | — | — | US | disclosed |
| US-9012531-B2 | Dental compositions comprising mixture of isocyanurate monomer and tricyclodecane monomer | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-04-21 | — | — | US | disclosed |
| US-20140220512-A1 | DENTAL COMPOSITIONS COMPRISING MIXTURE OF ISOCYANURATE MONOMER AND TRICYCLODECANE MONOMER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-08-07 | — | — | US | disclosed |
| US-8710113-B2 | Dental composition, kit of parts and use thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-04-29 | — | — | US | disclosed |
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-11-14 | — | — | US | disclosed |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303655-A1 | DENTAL COMPOSITION, METHOD OF PRODUCING AND USE THEREOF | PAM, PTMS, ACR | SMN1; SMN2 4797/4885ALDH1A1 2692/4885LMNA 489/4885 |
| US-20140220512-A1 | DENTAL COMPOSITIONS COMPRISING MIXTURE OF ISOCYANURATE MONOMER AND TRICYCLODECANE MONOMER | INTS9, INTS6, ERCC1 | SMN1; SMN2 2919/4885ALDH1A1 1049/4885LMNA 1118/4885 |
| US-20150238389-A1 | DENTAL COMPOSITIONS COMPRISING ETHYLENICALLY UNSATURATED ADDITION-FRAGMENTATION AGENT | NR4A1, RXRG, RXRA | SMN1; SMN2 3841/4885ALDH1A1 4052/4885LMNA 100/4885 |
| US-20130109777-A1 | DENTAL COMPOSITION, KIT OF PARTS AND USE THEREOF | KIT, KDM5C, PHAX | SMN1; SMN2 4651/4885ALDH1A1 2380/4885LMNA 57/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.