Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.43 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.43 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CERT1 | Q9Y5P4 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9468671 | 1.00 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2SOAT2SOAT1 | |
| SCHEMBL18377331 | 0.79 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2ASAH1LMNA | |
| SCHEMBL11158758 | 0.79 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2ASAH1LMNA | |
| SCHEMBL15955454 | 0.77 | SMN1; SMN2 (0.55) | NPC1RAB9ASMN1; SMN2ASAH1LMNA | |
| SCHEMBL10512429 | 0.76 | LMNA (0.52) | NPC1RAB9ASMN1; SMN2ASAH1LMNA | |
| SCHEMBL9545871 | 0.75 | EPHX2 (0.49) | SOAT2SOAT1FAAHEPHX2CNR1 | |
| SCHEMBL25365282 | 0.74 | ALDH1A1 (0.50) | NPC1RAB9ASMN1; SMN2SOAT2SOAT1 | |
| SCHEMBL16167176 | 0.74 | CYP1A2 (0.47) | SMN1; SMN2SOAT2SOAT1ASAH1LMNA | |
| SCHEMBL17764771 | 0.74 | CYP1A2 (0.47) | SMN1; SMN2SOAT2SOAT1ASAH1LMNA | |
| SCHEMBL16167086 | 0.74 | CYP1A2 (0.47) | SMN1; SMN2SOAT2SOAT1ASAH1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993025521-A1 | ARYL ALIPHATIC ACIDS | BOARD OF GOVERNORS OF WAYNE STATE UNIVERSITY (US) | 1993-12-23 | — | — | WO | disclosed |