Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | PNLIP | P16233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18377771 | 1.00 | CA12 (0.35) | CA12CA1CA2CA9ALOX5 | |
| SCHEMBL8269509 | 0.81 | NOS2 (0.39) | CA12CA1CA2CA9PNLIP | |
| SCHEMBL8955981 | 0.79 | TGFBR1 (0.49) | CA12CA1CA2CA9ALOX5 | |
| SCHEMBL18377626 | 0.79 | CA12 (0.35) | CA12CA1CA2CA9ALOX5 | |
| SCHEMBL24670989 | 0.73 | TSHR (0.41) | CA12CA1CA2CA9 | |
| SCHEMBL16539978 | 0.72 | TSHR (0.44) | CA12CA1CA2CA9 | |
| SCHEMBL16539979 | 0.72 | TSHR (0.44) | CA12CA1CA2CA9 | |
| SCHEMBL468839 | 0.71 | CA12 (0.42) | CA12CA1CA2CA9ALOX5 | |
| SCHEMBL38274 | 0.71 | CA12 (0.42) | CA12CA1CA2CA9ALOX5 | |
| SCHEMBL15148548 | 0.71 | CA12 (0.42) | CA12CA1CA2CA9ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017006295-A1 | HYDROXY FORMAMIDE DERIVATIVES AND THEIR USE | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-01-12 | — | — | WO | disclosed |