Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3579785 | 0.78 | TDP1 (0.49) | TDP1L3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL22854880 | 0.77 | RHOC (0.38) | TDP1KMT2AMEN1CYP3A4ALDH1A1 | |
| SCHEMBL4654059 | 0.77 | TDP1 (0.58) | TDP1L3MBTL1KMT2AMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL16654349 | 0.77 | TDP1 (0.48) | TDP1L3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL16722630 | 0.76 | PLAU (0.36) | KMT2AMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL27471133 | 0.76 | L3MBTL1 (0.50) | TDP1L3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL3208283 | 0.75 | TDP1 (0.59) | TDP1L3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL31255154 | 0.75 | TDP1 (0.59) | TDP1L3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL2278694 | 0.74 | TDP1 (0.58) | TDP1L3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL9290492 | 0.74 | TDP1 (0.58) | TDP1L3MBTL1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200230117-A1 | NOVEL SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN-2,3-DIOXYGENASE | IOMET PHARMA LTD. (GB) | 2020-07-23 | — | — | US | disclosed |
| US-20180186787-A1 | PHARMACEUTICAL COMPOUND | MERCK SHARP & DOHME CORP. (US) | 2018-07-05 | — | — | US | disclosed |
| WO-2017007700-A1 | PHARMACEUTICAL COMPOUND | IOMET PHARMA LTD. (GB) | 2017-01-12 | — | — | WO | disclosed |
| CN-100387127-C | Fungicides | AVENTIS CROPSCIENCE GMBH (DE) | 2008-05-14 | — | — | CN | disclosed |
| CN-1370046-A | Fungicidal agents | AVENTIS CROPSCIENCE GMBH (DE) | 2002-09-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200230117-A1 | NOVEL SUBSTITUTED IMIDAZOPYRIDINE COMPOUNDS AS INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND/OR TRYPTOPHAN-2,3-DIOXYGENASE | IDO1, IDO2, TDO2 | TDP1 92/4885L3MBTL1 4520/4885KMT2A 1209/4885 |
| US-20180186787-A1 | PHARMACEUTICAL COMPOUND | TDO2, IDO2, IDO1 | TDP1 935/4885L3MBTL1 4793/4885KMT2A 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.