Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18379064 | 0.92 | ESR1 (0.50) | STAT3HIF1AAPPBCHEACHE | |
| SCHEMBL18378925 | 0.86 | APP (0.53) | STAT3HIF1AAPPBCHEACHE | |
| SCHEMBL18379009 | 0.84 | STAT3 (0.44) | STAT3HIF1AAPPBCHEACHE | |
| SCHEMBL18379210 | 0.84 | HTR1A (0.48) | STAT3HIF1AAPPBCHEACHE | |
| SCHEMBL18379189 | 0.84 | HTR1A (0.48) | STAT3HIF1AAPPBCHEACHE | |
| SCHEMBL18378894 | 0.84 | STAT3 (0.48) | STAT3HIF1AAPPBCHEACHE | |
| SCHEMBL18379185 | 0.83 | HTR1A (0.53) | STAT3HIF1AAPPBCHEACHE | |
| SCHEMBL18379119 | 0.81 | BCHE (0.48) | STAT3HIF1AAPPBCHEACHE | |
| SCHEMBL18378926 | 0.81 | STAT3 (0.45) | STAT3HIF1AAPPBCHEACHE | |
| SCHEMBL18470146 | 0.80 | MAPT (0.56) | MAPTALDH1A1HSD17B10ESR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200354356-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | UNIVERSITY OF UTAH | 2020-11-12 | — | — | US | disclosed |
| US-20180201612-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | UNIVERSITY OF UTAH | 2018-07-19 | — | — | US | disclosed |
| US-20180201612-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | UNIVERSITY OF UTAH | 2018-07-19 | — | — | US | disclosed |
| WO-2017008074-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2017-01-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200354356-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | NCS1, DAXX, CNDP2 | STAT3 4101/4885HIF1A 3544/4885APP 616/4885 |
| US-20180201612-A1 | SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES | NCS1, DAXX, CNDP2 | STAT3 4101/4885HIF1A 3544/4885APP 616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.