SCHEMBL18379249

SCHEMBL18379249

CCCCCCCCCCCCN1C(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)C1=O)c64)C(=O)N(CC1CCCN(C)C1)C5=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 6/20 0.45
▸ STAT3 P40763 1/20 0.45
▸ HIF1A Q16665 1/20 0.45
▸ CYP1B1 Q16678 4/20 0.41
▸ ABCB11 O95342 1/20 0.40
▸ CHRM2 P08172 1/20 0.40
▸ CHRM4 P08173 1/20 0.40
▸ CHRM5 P08912 1/20 0.40
▸ ADRA2A P08913 1/20 0.40
▸ CHRM1 P11229 1/20 0.40
▸ ADRA2B P18089 1/20 0.40
▸ CHRM3 P20309 1/20 0.40
▸ DRD1 P21728 1/20 0.40
▸ PTGS1 P23219 1/20 0.40
▸ SLC6A2 P23975 1/20 0.40
▸ ADRA1D P25100 1/20 0.40
▸ HTR2A P28223 1/20 0.40
▸ HTR2C P28335 1/20 0.40
▸ SLC6A4 P31645 1/20 0.40
▸ ADRA1A P35348 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18376158 0.90 TERT (0.51) TERTSTAT3HIF1ACYP1B1ABCB11
SCHEMBL18379186 0.88 STAT3 (0.48) TERTSTAT3HIF1ACYP1B1MEN1
SCHEMBL18927243 0.85 CYP1B1 (0.47) TERTSTAT3HIF1ACYP1B1ABCB11
SCHEMBL284967 0.81 STAT3 (0.65) TERTSTAT3HIF1APTGS1MEN1
SCHEMBL1105114 0.81 STAT3 (0.65) TERTSTAT3HIF1APTGS1MEN1
SCHEMBL18376159 0.81 STAT3 (0.65) TERTSTAT3HIF1APTGS1MEN1
SCHEMBL8071104 0.81 STAT3 (0.65) TERTSTAT3HIF1APTGS1MEN1
SCHEMBL418871 0.81 STAT3 (0.65) TERTSTAT3HIF1APTGS1MEN1
SCHEMBL18379137 0.81 STAT3 (0.65) TERTSTAT3HIF1APTGS1MEN1
SCHEMBL7485132 0.81 STAT3 (0.65) TERTSTAT3HIF1APTGS1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11022592-B2 Chemical self-doping of one-dimensional organic nanomaterials for high conductivity application in chemiresistive sensing gas or vapor UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2021-06-01 — — US disclosed
US-20200354356-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH 2020-11-12 — — US disclosed
US-20180201612-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH 2018-07-19 — — US disclosed
US-20180201612-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH 2018-07-19 — — US disclosed
WO-2017142609-A2 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRESISTIVE SENSING GAS OR VAPOR UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2017-08-24 — — WO disclosed
US-20170160252-A1 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRSISTIVE SENSING GAS OR VAPOR UNIVERSITY OF UTAH 2017-06-08 — — US disclosed
US-20170160252-A1 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRSISTIVE SENSING GAS OR VAPOR UNIVERSITY OF UTAH 2017-06-08 — — US disclosed
WO-2017008074-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2017-01-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354356-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES NCS1, DAXX, CNDP2 TERT 3724/4885STAT3 4101/4885HIF1A 3544/4885
US-20170160252-A1 CHEMICAL SELF-DOPING OF ONE-DIMENSIONAL ORGANIC NANOMATERIALS FOR HIGH CONDUCTIVITY APPLICATION IN CHEMIRSISTIVE SENSING GAS OR VAPOR DRD1, DRD4, DNER TERT 806/4885STAT3 1719/4885HIF1A 1831/4885
US-11022592-B2 Chemical self-doping of one-dimensional organic nanomaterials for high conductivity application in chemiresistive sensing gas or vapor DRD1, DRD2, DNER TERT 839/4885STAT3 1876/4885HIF1A 2131/4885
US-20180201612-A1 SENSOR COMPOUNDS AND ASSOCIATED METHODS AND DEVICES NCS1, DAXX, CNDP2 TERT 3724/4885STAT3 4101/4885HIF1A 3544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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