Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.67 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.64 |
| ▸ | QPCT | Q16769 | 1/20 | 0.53 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.53 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.53 |
| ▸ | ITGAL | P20701 | 3/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27675779 | 0.93 | EPHX2 (0.60) | EPHX2SLC6A5QPCTQPCTLITGB2 | |
| SCHEMBL29615190 | 0.93 | EPHX2 (0.60) | EPHX2SLC6A5QPCTQPCTLITGB2 | |
| SCHEMBL3057446 | 0.93 | EPHX2 (0.60) | EPHX2SLC6A5QPCTQPCTLITGB2 | |
| SCHEMBL18676311 | 0.85 | SLC6A5 (0.59) | EPHX2SLC6A5QPCTQPCTLITGB2 | |
| SCHEMBL19077814 | 0.85 | SLC6A5 (0.79) | EPHX2SLC6A5ITGB2ICAM1ITGAL | |
| SCHEMBL28459868 | 0.85 | SLC15A2 (0.53) | EPHX2SLC6A5QPCTQPCTLITGB2 | |
| SCHEMBL29152624 | 0.84 | QPCT (0.57) | EPHX2SLC6A5QPCTQPCTLITGB2 | |
| SCHEMBL29152626 | 0.84 | QPCT (0.57) | EPHX2SLC6A5QPCTQPCTLITGB2 | |
| SCHEMBL9664616 | 0.84 | SLC6A5 (0.85) | EPHX2SLC6A5ITGB2ICAM1ITGAL | |
| SCHEMBL19059414 | 0.84 | SLC6A5 (0.70) | EPHX2SLC6A5ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170183318-A1 | AMIDE COMPOUNDS, METHODS FOR PREPARATION, AND USE THEREOF AS AGENTS FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY RNA- AND/OR DNA-CONTAINING VIRUSES, AND CONCOMITANT DISEASES | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) | 2017-06-29 | — | — | US | disclosed |
| US-20170183318-A1 | AMIDE COMPOUNDS, METHODS FOR PREPARATION, AND USE THEREOF AS AGENTS FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY RNA- AND/OR DNA-CONTAINING VIRUSES, AND CONCOMITANT DISEASES | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU "PHARMENTERPRISES" (RU) | 2017-06-29 | — | — | US | disclosed |
| EP-3118211-A1 | AMIDE COMPOUNDS AND METHODS FOR THE PRODUCTION AND USE THEREOF | Obschestvo S Ogranichennoi Otvetstennostiyu "Pharmenterprises" (RU) | 2017-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183318-A1 | AMIDE COMPOUNDS, METHODS FOR PREPARATION, AND USE THEREOF AS AGENTS FOR THE TREATMENT AND PREVENTION OF DISEASES CAUSED BY RNA- AND/OR DNA-CONTAINING VIRUSES, AND CONCOMITANT DISEASES | ACE, ACE2, MCTS1 | EPHX2 3269/4885SLC6A5 3373/4885QPCT 3850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.