Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.79 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.57 |
| ▸ | ITGAL | P20701 | 3/20 | 0.57 |
| ▸ | FAAH | O00519 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.55 |
| ▸ | CNR2 | P34972 | 2/20 | 0.55 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.47 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9664616 | 0.96 | SLC6A5 (0.85) | SLC6A5EPHX2ITGB2ICAM1ITGAL | |
| SCHEMBL9664374 | 0.95 | SLC6A5 (0.87) | SLC6A5EPHX2ITGB2ICAM1ITGAL | |
| SCHEMBL15650015 | 0.95 | SLC6A5 (0.87) | SLC6A5EPHX2ITGB2ICAM1ITGAL | |
| SCHEMBL28341177 | 0.95 | SLC6A5 (0.87) | SLC6A5EPHX2ITGB2ICAM1ITGAL | |
| SCHEMBL4348859 | 0.95 | SLC6A5 (0.87) | SLC6A5EPHX2ITGB2ICAM1ITGAL | |
| SCHEMBL15649758 | 0.95 | SLC6A5 (0.87) | SLC6A5EPHX2ITGB2ICAM1ITGAL | |
| SCHEMBL17204083 | 0.95 | SLC6A5 (0.87) | SLC6A5EPHX2ITGB2ICAM1ITGAL | |
| SCHEMBL17817155 | 0.95 | SLC6A5 (0.87) | SLC6A5EPHX2ITGB2ICAM1ITGAL | |
| SCHEMBL22034112 | 0.95 | SLC6A5 (0.87) | SLC6A5EPHX2ITGB2ICAM1ITGAL | |
| SCHEMBL13279669 | 0.95 | SLC6A5 (0.87) | SLC6A5EPHX2ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573895-A | Novel 5-acylsulfanyl-histidine compounds as precursors for the corresponding 5-sulfanylhistidines and disulfides thereof | 特瑞海德公司 | 2017-04-19 | — | — | CN | claimed |
| US-9926300-B2 | 5-acylsulfanyl-histidine compounds as precursors of the corresponding 5-sulfanylhistidines and their disulfides | TETRAHEDRON (FR) | 2018-03-27 | — | — | US | disclosed |
| US-9926300-B2 | 5-acylsulfanyl-histidine compounds as precursors of the corresponding 5-sulfanylhistidines and their disulfides | TETRAHEDRON (FR) | 2018-03-27 | — | — | US | disclosed |
| US-20170190691-A1 | NOVEL 5-ACYLSULFANYL-HISTIDINE COMPOUNDS AS PRECURSORS OF THE CORRESPONDING 5-SULFANYLHISTIDINES AND THEIR DISULFIDES | TETRAHEDRON (FR) | 2017-07-06 | — | — | US | disclosed |
| US-20170190691-A1 | NOVEL 5-ACYLSULFANYL-HISTIDINE COMPOUNDS AS PRECURSORS OF THE CORRESPONDING 5-SULFANYLHISTIDINES AND THEIR DISULFIDES | TETRAHEDRON (FR) | 2017-07-06 | — | — | US | disclosed |
| CN-106573895-A | Novel 5-acylsulfanyl-histidine compounds as precursors for the corresponding 5-sulfanylhistidines and disulfides thereof | 特瑞海德公司 | 2017-04-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190691-A1 | NOVEL 5-ACYLSULFANYL-HISTIDINE COMPOUNDS AS PRECURSORS OF THE CORRESPONDING 5-SULFANYLHISTIDINES AND THEIR DISULFIDES | AHCYL1, CBS, H1-5 | SLC6A5 363/4885EPHX2 824/4885ITGB2 3128/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.