⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27783583 | 0.69 | — | — | |
| SCHEMBL977221 | 0.69 | THRB (0.33) | — | |
| SCHEMBL22346066 | 0.68 | LMNA (0.41) | — | |
| SCHEMBL7135804 | 0.67 | THRB (0.32) | — | |
| SCHEMBL3623773 | 0.66 | THRB (0.35) | — | |
| SCHEMBL2042055 | 0.65 | LMNA (0.35) | — | |
| SCHEMBL5170974 | 0.65 | THRB (0.31) | — | |
| SCHEMBL7617707 | 0.64 | — | — | |
| SCHEMBL183067 | 0.64 | — | — | |
| SCHEMBL332697 | 0.64 | THRB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040015-A1 | BIOCOMPATIBLE COMPOSITE AND ITS USE | PURAC BIOCHEM BV (NL) | 2012-02-16 | — | — | US | disclosed |
| EP-2243500-B1 | Biocompatible composite and its use | VIVOXID OY (FI) | 2012-01-04 | — | — | EP | disclosed |