SCHEMBL18382467

SCHEMBL18382467

CC(CCCOCC(C)c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.47
TAAR1 Q96RJ0 3/20 0.44
TRPA1 O75762 3/20 0.41
AOC3 Q16853 2/20 0.40
CASR P41180 1/20 0.38
ALDH1A1 P00352 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8750460 0.90 RIPK1 (0.52) RIPK1TAAR1TRPA1AOC3ALDH1A1
SCHEMBL22456917 0.85 ALDH1A1 (0.44) RIPK1TAAR1TRPA1AOC3ALDH1A1
SCHEMBL8750373 0.85 RIPK1 (0.50) RIPK1TAAR1TRPA1AOC3ALDH1A1
SCHEMBL22050524 0.84 TAAR1 (0.50) RIPK1TAAR1TRPA1AOC3CASR
SCHEMBL16800096 0.84 SMN1; SMN2 (0.44) RIPK1TAAR1TRPA1AOC3ALDH1A1
SCHEMBL12519814 0.83 TAAR1 (0.45) RIPK1TAAR1TRPA1AOC3CASR
SCHEMBL12519823 0.83 TAAR1 (0.45) RIPK1TAAR1TRPA1AOC3CASR
SCHEMBL12519822 0.82 IDO1 (0.47) TAAR1
SCHEMBL12519824 0.82 NPC1 (0.43) TAAR1
SCHEMBL12519813 0.82 IDO1 (0.47) TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170018801-A1 BRUSH BLOCK COPOLYMER ELECTROLYTES AND ELECTROCATALYST COMPOSITIONS CALIFORNIA INSTITUTE OF TECHNOLOGY 2017-01-19 US disclosed