Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18391717 | 0.90 | TSHR (0.38) | GAASMN1; SMN2KMT2ATSHRLMNA | |
| SCHEMBL18391720 | 0.81 | TSHR (0.38) | GAASMN1; SMN2KMT2ATSHRLMNA | |
| SCHEMBL18384641 | 0.77 | TSHR (0.45) | TSHRLMNAPOLBKDM4EMAPK1 | |
| SCHEMBL18384529 | 0.77 | GAA (0.42) | GAASMN1; SMN2KMT2APOLBKDM4E | |
| SCHEMBL18384642 | 0.74 | LMNA (0.39) | TSHRLMNAPOLBKDM4EALDH1A1 | |
| SCHEMBL18384628 | 0.74 | KDM4E (0.46) | GAASMN1; SMN2KMT2ATSHRLMNA | |
| SCHEMBL18384560 | 0.74 | GAA (0.43) | GAASMN1; SMN2KMT2APOLBKDM4E | |
| SCHEMBL18384643 | 0.72 | MMP3 (0.40) | GAASMN1; SMN2KMT2ATSHRLMNA | |
| SCHEMBL18384630 | 0.70 | LMNA (0.57) | SMN1; SMN2KMT2ALMNAPOLBKDM4E | |
| SCHEMBL18391655 | 0.70 | TSHR (0.37) | KMT2ATSHRLMNAPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170015677-A1 | NEW TRICYCLIC QUINONE DERIVATIVE | BOSTON BIOMEDICAL, INC. (US) | 2017-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170015677-A1 | NEW TRICYCLIC QUINONE DERIVATIVE | NQO1, SQOR, SULT1E1 | GAA 2327/4885SMN1; SMN2 3746/4885KMT2A 1489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.