Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.46 |
| ▸ | PAM | P19021 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.45 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2608077 | 0.82 | FOS (0.50) | PAMNFE2L2GRIK1GRIK2LMNA | |
| SCHEMBL5311091 | 0.82 | PAM (0.68) | HSD11B1TNFRSF1APAMNFE2L2GRIK1 | |
| SCHEMBL5311088 | 0.82 | PAM (0.68) | HSD11B1TNFRSF1APAMNFE2L2GRIK1 | |
| SCHEMBL18598225 | 0.81 | HSD11B1 (0.53) | HSD11B1TNFRSF1ATRPA1NFE2L2GRIK1 | |
| SCHEMBL9027791 | 0.81 | HSD11B1 (0.53) | HSD11B1TNFRSF1ATRPA1NFE2L2GRIK1 | |
| SCHEMBL31396664 | 0.81 | HSD11B1 (0.52) | HSD11B1TNFRSF1APAMNFE2L2GRIK1 | |
| SCHEMBL8984593 | 0.81 | CYP1A2 (0.57) | PAMGRIK1GRIK2LMNAMAOB | |
| SCHEMBL5727634 | 0.81 | CYP1A2 (0.57) | PAMGRIK1GRIK2LMNAMAOB | |
| SCHEMBL827256 | 0.80 | PAM (0.70) | PAMLMNAMAOBMAPTMAOA | |
| SCHEMBL827257 | 0.80 | PAM (0.70) | PAMLMNAMAOBMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321287-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010010014-A1 | 4,5-DIHYDRO-OXAZOL-2-YL DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-01-28 | — | — | WO | disclosed |
| EP-1347952-A4 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2005-10-26 | — | — | EP | disclosed |
| EP-1347952-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | Dow AgroSciences LLC (US) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002046142-A1 | ARYL AND HETEROARYLCYCLOPROPYL OXIME ETHERS AND THEIR USE AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2002-06-13 | — | — | WO | disclosed |