SCHEMBL18386460

SCHEMBL18386460

COC(C)(C)C1OC(CO)C(O)C(OC2OC(C(=O)O)C(OC(C)(C)C)C(O)C2O)C1NC(C)=O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ LGALS3 P17931 6/20 0.40
▸ LGALS8 O00214 1/20 0.40
▸ LGALS4 P56470 1/20 0.40
▸ MAPK1 P28482 2/20 0.40
▸ MDK P21741 3/20 0.38
▸ BDNF P23560 3/20 0.38
▸ PTN P21246 2/20 0.38
▸ CD69 Q07108 1/20 0.38
▸ LGALS9 O00182 1/20 0.37
▸ ALDH1A1 P00352 1/20 0.36
▸ THRB P10828 1/20 0.36
▸ LGALS1 P09382 1/20 0.36
▸ LGALS7; LGALS7B P47929 1/20 0.36
▸ CHIA Q9BZP6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22137175 0.91 LGALS3 (0.42) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL20290392 0.89 LGALS3 (0.42) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL19221227 0.89 LGALS3 (0.42) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL19852803 0.88 LGALS3 (0.45) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL26479163 0.88 MDK (0.45) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL23322444 0.84 LGALS3 (0.43) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL18608138 0.84 LGALS3 (0.43) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL18608226 0.84 LGALS3 (0.43) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL25645148 0.83 LGALS3 (0.51) LGALS3LGALS8LGALS4MAPK1MDK
SCHEMBL19818421 0.83 BDNF (0.42) LGALS3LGALS8LGALS4MAPK1MDK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10023658-B2 Conjugates of oligomer of hyaluronic acid or of a salt thereof, method of preparation thereof and use thereof CONTIPRO A.S. (CZ) 2018-07-17 — — US disclosed
US-20170015759-A1 Conjugates of Oligomer of Hyaluronic Acid or of a Salt Thereof, Method of Preparation Thereof and Use Thereof CONTIPRO A.S. (CZ) 2017-01-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170015759-A1 Conjugates of Oligomer of Hyaluronic Acid or of a Salt Thereof, Method of Preparation Thereof and Use Thereof CD44, MUC1, SLC17A5 LGALS3 577/4885LGALS8 388/4885LGALS4 665/4885
US-10023658-B2 Conjugates of oligomer of hyaluronic acid or of a salt thereof, method of preparation thereof and use thereof CD44, MUC1, SLC17A5 LGALS3 577/4885LGALS8 388/4885LGALS4 665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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