Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19441245 | 0.79 | TDP1 (0.42) | GAASMN1; SMN2KDM4EMEN1USP2 | |
| SCHEMBL23709740 | 0.79 | TDP1 (0.42) | GAASMN1; SMN2KDM4EMEN1USP2 | |
| SCHEMBL20045386 | 0.77 | TDP1 (0.43) | KCNH2GAASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL24999915 | 0.76 | KCNH2 (0.35) | KCNH2GAASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL22542275 | 0.75 | CNR1 (0.33) | SMPD1CNR2SMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL19139260 | 0.75 | CNR1 (0.33) | SMPD1CNR2SMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL12425628 | 0.75 | HSD11B1 (0.39) | KCNH2SMN1; SMN2KDM4EMEN1ALDH1A1 | |
| SCHEMBL21719506 | 0.73 | CNR1 (0.33) | SMPD1CNR2SMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL23583957 | 0.73 | CNR1 (0.33) | SMPD1CNR2SMN1; SMN2ALDH1A1CNR1 | |
| SCHEMBL22273334 | 0.73 | CNR1 (0.33) | SMPD1CNR2SMN1; SMN2ALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170014419-A1 | MEDICAMENT FOR SUPPRESSING MALIGNANT TUMOR METASTASIS | NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER (JP) | 2017-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170014419-A1 | MEDICAMENT FOR SUPPRESSING MALIGNANT TUMOR METASTASIS | AGTR2, MME, AGTR1 | SMPD1 1277/4885KCNH2 3220/4885CNR2 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.