Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.46 |
| ▸ | TUBB | P07437 | 2/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.46 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.46 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18392173 | 0.87 | ABCG2 (0.54) | ABCG2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL18392204 | 0.86 | ABCG2 (0.57) | ABCG2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL18392164 | 0.85 | ESR1 (0.54) | ALDH1A1HPGDHSD17B10MEN1MAPT | |
| SCHEMBL18392216 | 0.83 | PTGS2 (0.48) | ALDH1A1HPGDKDM4EMEN1MAPT | |
| SCHEMBL18392172 | 0.82 | PDE4B (0.59) | ALDH1A1HPGDKDM4EHSD17B10MEN1 | |
| SCHEMBL20365539 | 0.80 | ESR1 (0.42) | HPGDGPR84PTGS2 | |
| SCHEMBL3333256 | 0.79 | MEN1 (0.50) | ABCG2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL18392199 | 0.78 | PDE4B (0.52) | ALDH1A1KDM4EHSD17B10MEN1MAPT | |
| SCHEMBL7262282 | 0.77 | ABCG2 (0.55) | ABCG2ALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL19717689 | 0.77 | DYRK1A (0.63) | ALDH1A1HPGDKDM4EHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3319940-B1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | UNIV BRAUNSCHWEIG TECH (DE) | 2019-05-29 | — | — | EP | disclosed |
| EP-3319940-B1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | UNIV BRAUNSCHWEIG TECH (DE) | 2019-05-29 | — | — | EP | disclosed |
| US-10287271-B2 | Indole compounds having antiprotozoal activity and its use as well as methods for producing the same | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2019-05-14 | — | — | US | disclosed |
| US-10287271-B2 | Indole compounds having antiprotozoal activity and its use as well as methods for producing the same | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2019-05-14 | — | — | US | disclosed |
| US-20180194750-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2018-07-12 | — | — | US | disclosed |
| US-20180194750-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2018-07-12 | — | — | US | disclosed |
| WO-2017008826-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | TECHNISCHE UNIVERSITAET BRAUNSCHWEIG (DE) | 2017-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194750-A1 | NEW INDOLE COMPOUNDS HAVING ANTIPROTOZOAL ACTIVITY AND ITS USE AS WELL AS METHODS FOR PRODUCING THE SAME | IDO1, IDO2, INMT | ABCG2 354/4885ALDH1A1 774/4885HPGD 140/4885 |
| US-10287271-B2 | Indole compounds having antiprotozoal activity and its use as well as methods for producing the same | IDO1, IDO2, INMT | ABCG2 551/4885ALDH1A1 638/4885HPGD 130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.