Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ADK | P55263 | 11/20 | 0.46 |
| ▸ | SRC | P12931 | 5/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PAK4 | O96013 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | CSF1R | P07333 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | PRKACA | P17612 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | LTK | P29376 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18393434 | 1.00 | MTOR (0.47) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL16236916 | 0.84 | MTOR (0.50) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL19743546 | 0.81 | MTOR (0.52) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL16237288 | 0.80 | SRC (0.59) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL30120727 | 0.80 | ABL1 (0.48) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL16236082 | 0.80 | ABL1 (0.48) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL20981824 | 0.79 | SRC (0.51) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL13857873 | 0.79 | ADK (0.45) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL29388723 | 0.79 | ADK (0.47) | MTORRAB9AADKSRCEGFR | |
| SCHEMBL19743265 | 0.79 | SRC (0.52) | MTORRAB9AADKSRCEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3120852-A1 | PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR IMMUNE DISEASES | Taiho Pharmaceutical Co., Ltd. (JP) | 2017-01-25 | — | — | EP | disclosed |