Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 20/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 20/20 | 0.56 |
| ▸ | GABRP | O00591 | 19/20 | 0.56 |
| ▸ | GABRD | O14764 | 19/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 19/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 19/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 19/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 19/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 19/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 19/20 | 0.56 |
| ▸ | GABRA4 | P48169 | 19/20 | 0.56 |
| ▸ | GABRE | P78334 | 19/20 | 0.56 |
| ▸ | GABRA6 | Q16445 | 19/20 | 0.56 |
| ▸ | GABRG1 | Q8N1C3 | 19/20 | 0.56 |
| ▸ | GABRG3 | Q99928 | 19/20 | 0.56 |
| ▸ | GABRQ | Q9UN88 | 19/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3827692 | 0.93 | GABRP (0.51) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL7779071 | 0.91 | GABRP (0.51) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL20089290 | 0.90 | GABRP (0.53) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL33214 | 0.87 | GABRP (0.52) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL4751430 | 0.85 | GABRP (0.53) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL7028353 | 0.84 | GABRP (0.49) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL7715369 | 0.84 | GABRP (0.62) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL7244399 | 0.84 | GABRP (0.48) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL7028348 | 0.84 | GABRP (0.48) | GABRA2GABRB2GABRPGABRDGABRA1 | |
| SCHEMBL12473393 | 0.83 | GABRP (0.57) | GABRA2GABRB2GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11134685-B2 | Compositions and uses thereof for controlling ectoparasites in non-human mammals | Ceva Santé Animale (FR) | 2021-10-05 | — | — | US | disclosed |
| US-20200163339-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Santé Animale (FR) | 2020-05-28 | — | — | US | disclosed |
| US-20180213790-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Santé Animale (FR) | 2018-08-02 | — | — | US | disclosed |
| EP-3324955-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAIN MAMMALS | Ceva Sante Animale (FR) | 2018-05-30 | — | — | EP | disclosed |
| EP-3259990-A1 | METHODS FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Sante Animale (FR) | 2017-12-27 | — | — | EP | disclosed |
| WO-2017017021-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAIN MAMMALS | CEVA SANTE ANIMALE (FR) | 2017-02-02 | — | — | WO | disclosed |
| EP-3120846-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | Ceva Sante Animale (FR) | 2017-01-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11134685-B2 | Compositions and uses thereof for controlling ectoparasites in non-human mammals | NISCH, NAMPT, TYR | GABRA2 3449/4885GABRB2 3887/4885GABRP 2904/4885 |
| US-20180213790-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | NISCH, NAMPT, TYR | GABRA2 3449/4885GABRB2 3887/4885GABRP 2904/4885 |
| US-20200163339-A1 | COMPOSITIONS AND USES THEREOF FOR CONTROLLING ECTOPARASITES IN NON-HUMAN MAMMALS | NISCH, NAMPT, TYR | GABRA2 3449/4885GABRB2 3887/4885GABRP 2904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.