SCHEMBL33214

SCHEMBL33214

NC(=S)c1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1[S+]([O-])C(F)(F)F

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GABRP O00591 19/20 0.52
GABRD O14764 19/20 0.52
GABRA1 P14867 19/20 0.52
GABRB1 P18505 19/20 0.52
GABRG2 P18507 19/20 0.52
GABRB3 P28472 19/20 0.52
GABRA5 P31644 19/20 0.52
GABRA3 P34903 19/20 0.52
GABRA2 P47869 19/20 0.52
GABRB2 P47870 19/20 0.52
GABRA4 P48169 19/20 0.52
GABRE P78334 19/20 0.52
GABRA6 Q16445 19/20 0.52
GABRG1 Q8N1C3 19/20 0.52
GABRG3 Q99928 19/20 0.52
GABRQ Q9UN88 19/20 0.52
ALDH1A1 P00352 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4797885 0.93 GABRP (0.48) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL4751430 0.91 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7779071 0.90 GABRP (0.51) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7667746 0.88 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL677097 0.88 GABRP (0.41) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7028353 0.88 GABRP (0.49) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL18393472 0.87 GABRA2 (0.56) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL15337137 0.86 GABRP (0.37) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL20089290 0.86 GABRP (0.53) GABRPGABRDGABRA1GABRB1GABRG2
SCHEMBL7675454 0.85 GABRP (0.46) GABRPGABRDGABRA1GABRB1GABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130137571-A1 Crystalline Modification of Fipronil BASF SE (DE) 2013-05-30 US claimed
US-20130045996-A1 COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS BAYER ANIMAL HEALTH GMBH (DE) 2013-02-21 US claimed
US-20100093531-A1 Pesticidal Mixtures Based on Azolopyrimidinylamines Derivatives and Insecticides BASF SE (DE) 2010-04-15 US claimed
US-20100016398-A1 COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS BAYER ANIMAL HEALTH GMBH (DE) 2010-01-21 US claimed
US-20090312387-A1 COMPOSITION FOR CONTROLLING PARASITES ON ANIMALS BAYER ANIMAL HEALTH GMBH (DE) 2009-12-17 US claimed
US-20210161136-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2021-06-03 US disclosed
US-20210161137-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds BASF SE (DE) 2021-06-03 US disclosed
US-10888094-B2 Pesticidal active mixtures comprising isoxazoline compounds I BASF SE (DE) 2021-01-12 US disclosed
US-10772322-B2 Use of polymer particles containing insecticide in order to improve the soil mobility of insecticides, insecticide formulas, polymer particles containing insecticide, and method for pest control BASF SE (DE) 2020-09-15 US disclosed
EP-3150068-B1 SEED TREATMENT COMPOSITIONS AND METHODS BASF SE (DE) 2019-10-09 EP disclosed
US-20190166843-A1 Pesticidal Active Mixtures Comprising Isoxazoline Compounds I BASF SE (DE) 2019-06-06 US disclosed
US-10231455-B2 Pesticidal active mixtures comprising isoxazoline compounds I BASF SE (DE) 2019-03-19 US disclosed
WO-2007060120-A1 INDANYL-AND TETRAHYDRONAPHTYL-AMINO-THIOUREA COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE (DE) 2007-05-31 WO disclosed
WO-2007051814-A1 BIOCIDAL STRUCTURAL BARRIER (BSB) SEP INNOVATERM (FR) 2007-05-10 WO disclosed
WO-2007051756-A1 CRYSTALLINE MODIFICATION OF N-ETHYL-2,2-DICHLORO-1-METHYLCYCLOPROPANE-CARBOXAMIDE-2-(2,6-DICHLORO- ALPHA,ALPHA,ALPHA -TRIFLUORO-P-TOLYL)HYDRAZONE BASF SE (DE) 2007-05-10 WO disclosed
WO-2007045588-A1 ISOTHIAZOLOPYRIDIN-3-YLENAMINES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2007-04-26 WO disclosed
WO-2007017433-A2 PESTICIDAL MIXTURES BASF SE (DE) 2007-02-15 WO disclosed
WO-2007014899-A1 DICYANO ALKANOIC ACID AMIDES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2007-02-08 WO disclosed
WO-2006125641-A2 PYRIDINE COMPOUNDS FOR COMBATING ARTHROPOD PESTS AND NEMATODES BASF AKTIENGESELLSCHAFT (DE) 2006-11-30 WO disclosed
WO-2006097489-A1 BIPHENYL-N-(4-PYRIDYL) METHYLSUFONAMIDES BASF AKTIENGESELLSCHAFT (DE) 2006-09-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210161137-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CHRM3, CHRM5, CHRM2 GABRP 500/4885GABRD 631/4885GABRA1 387/4885
US-20100093531-A1 Pesticidal Mixtures Based on Azolopyrimidinylamines Derivatives and Insecticides DDT, INMT, PNMT GABRP 907/4885GABRD 2124/4885GABRA1 1035/4885
US-20100016398-A1 COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS CYCS, CYP3A43, CDIPT GABRP 68/4885GABRD 346/4885GABRA1 385/4885
US-20190166843-A1 Pesticidal Active Mixtures Comprising Isoxazoline Compounds I CHRM3, CHRM5, CACNA1C GABRP 255/4885GABRD 363/4885GABRA1 251/4885
US-20130045996-A1 COMBINATION PRODUCT FOR CONTROLLING PARASITES ON ANIMALS CYCS, CYP3A43, CDIPT GABRP 68/4885GABRD 346/4885GABRA1 385/4885
US-20210161136-A1 Pesticidal Mixtures Comprising Cyanosulfoximine Compounds CHRM3, CHRM5, CHRM2 GABRP 500/4885GABRD 631/4885GABRA1 387/4885
US-20130137571-A1 Crystalline Modification of Fipronil FIP1L1, PTMS, FIBP GABRP 845/4885GABRD 3657/4885GABRA1 2202/4885
US-10888094-B2 Pesticidal active mixtures comprising isoxazoline compounds I CHRM3, CHRM5, CACNA1C GABRP 255/4885GABRD 363/4885GABRA1 251/4885
US-10772322-B2 Use of polymer particles containing insecticide in order to improve the soil mobility of insecticides, insecticide formulas, polymer particles containing insecticide, and method for pest control PIR, CBR3, GSR GABRP 170/4885GABRD 300/4885GABRA1 790/4885
US-10231455-B2 Pesticidal active mixtures comprising isoxazoline compounds I CHRM3, CHRM5, CACNA1C GABRP 255/4885GABRD 363/4885GABRA1 251/4885
US-20090312387-A1 COMPOSITION FOR CONTROLLING PARASITES ON ANIMALS CYCS, PTMS, PLCB3 GABRP 687/4885GABRD 3073/4885GABRA1 2122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.